63119-27-7
63119-27-7 结构式
基本信息
中文别名
阿尼扎芬 英文别名
LY-122512anitrazafen
5,6-Bis(p-methoxyphenyl)-3-methyl-1,2,4-triazine
5,6-Bis(4-methoxyphenyl)-3-methyl-1,2,4-triazine
1,2,4-Triazine, 5,6-bis(4-methoxyphenyl)-3-methyl-
物理化学性质
沸点482.8±55.0 °C(Predicted)
密度1.164±0.06 g/cm3(Predicted)
储存条件-20°C储存
溶解度溶于二甲基亚砜
酸度系数(pKa)1.85±0.63(Predicted)
常见问题列表
生物活性
Anitrazafen 是一种局部有效的抗炎剂。体内研究
Anitrazafen is a topically effective antiinflammatory agent. The disposition of 14 C in normal and in bile-duct cannulated rats after oral administration of a single dose of 25 mg/kg of [3- 14 C]Anitrazafen shows the drug to be well absorbed from the gastro-intestinal tract and biliary excretion to be the major route of elimination of drug and/or metabolites. Plasma concentrations of total 14 C after subcutaneous administration of [3- 14 C]Anitrazafen in corn oil solution are about one half those found after oral administration.