63631-36-7
63631-36-7 结构式
基本信息
中文别名
化合物 T10390化合物ASPERPHENAMATE
英文别名
AuranamideASPERPHENAMATE
N-Benzoyl-L-phenylalanine (S)-2-benzoylamino-3-phenylpropyl ester
(2S)-2-(Benzoylamino)-3-phenylpropanoic acid (2S)-2-(benzoylamino)-3-phenylpropyl ester
物理化学性质
储存条件-20°C储存
溶解度DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
形态固体
颜色White to off-white
常见问题列表
生物活性
Asperphenamate 是来自Aspergillus flatiipes 的真菌代谢物，具有抗肿瘤活性，其对 T47D、MDA-MB-231 和 HL-60 细胞的IC50 值分别为 92.3 μM、96.5 μM 和97.9 μM。体外研究
Asperphenamate can inhibit cancer cell proliferation by fully inducing autophagy. asperphenamate showed inhibition effects against cathepsin L. At the same time, it also displayed weak inhibitory ability against cathepsin S.