65023-16-7
中文名称
BOMETOLOL HYDROCHLORIDE
英文名称
Bometolol Hydrochloride
CAS
65023-16-7
分子式
C25H33ClN2O7
分子量
509
MOL 文件
65023-16-7.mol
![65023-16-7 结构式](/CAS/20211123/GIF/65023-16-7.gif)
常见问题列表
生物活性
Bometolol Hydrochloride 是一种 beta-adrenergic 阻滞剂,可用于高血压等心血管疾病的研究。靶点
Beta-adrenergic receptor
体内研究
Bometolol (10-30 mg/kg, p.o.) lowers the blood pressure dose-dependently in spontaneously hypertensive rats, deoxycorticosterone and salt hypertensive rats and two kindey, one clip hypertensive rats. In subchronic study, Bometolol (10-30 mg/kg, or 100-300 mg/kg, p.o.) dose-dependently decreases heart rate, plasma renin activity, heart and kindey weitht and incidence of vascular lesion, but shows no antihypertensive effects in all the hypertensive rats.