应用领域
用途1
The indole derivative of Hymenialdisine, a potent inhibitor of a variety of kinases including MEK-1, GSK-3螔, and CKI. It also exhibits inhibition of the G2 cell cycle checkpoint at the micromolar con
centrations. This compound exhibits very potent inhibition of Chk2 activity in the low nanomolar range (IC50=8nM). Exhibits an increased selectivity for the checkpoint kinases over natural Hymeniald
isine.