71902-47-1
中文名称
9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E,17Z-TRIEN-1-OIC ACID
英文名称
9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E,17Z-TRIEN-1-OIC ACID
CAS
71902-47-1
分子式
C20H30O5
分子量
350.45
MOL 文件
71902-47-1.mol
71902-47-1 结构式
基本信息
中文别名
9Α,15S-二羟基-11-氧代-前列腺素5Z,13E,17Z-三烯-1-油酸 英文别名
PGD3PROSTAGLANDIN D3
Prostaglandin D3
ANOICLBSJIMQTA-WXGBOJPQSA-N
Prostaglandin D3 Exclusive
9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E,17Z-TRIEN-1-OIC ACID
(5Z,13E,15S,17Z)-9α,15-Dihydroxy-11-oxoprosta-5,13,17-trien-1-oic acid
(Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]-3-oxocyclopentyl]hept-5-enoic acid
物理化学性质
储存条件-20°C储存
溶解度DMF: >100 mg/ml (from PGD2); DMSO: >50 mg/ml (from PGD2); Ethanol: >75 mg/ml (from PGD2); PBS pH 7.2: >5 mg/ml (from PGD2)
应用领域
用途一
Prostaglandin D3 (PGD3) is produced by the metabolism of EPA via the COX pathway. It is equipotent to PGD2 in decreasing systemic blood pressure in rats and in decreasing intraocular pressure in rabbits. However, it is 3-5 times more potent than PGD2 in the inhibition of ADP-induced human platelet aggregation.[Cayman Chemical]