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731006-86-3

中文名称 4-[3-[2-[[4-(乙酰氨基)苯基]硫代]乙酰]-2,5-二甲基-1H-吡咯-1-基]苯甲酸甲酯
英文名称 Benzoic acid, 4-[3-[2-[[4-(acetylamino)phenyl]thio]acetyl]-2,5-dimethyl-1H-pyrrol-1-yl]-, methyl ester
CAS 731006-86-3
分子式 C24H24N2O4S
分子量 436.52
MOL 文件 731006-86-3.mol
更新日期 2024/06/20 21:07:18
731006-86-3 结构式 731006-86-3 结构式

基本信息

中文别名
4-[3-[2-[[4-(乙酰氨基)苯基]硫代]乙酰]-2,5-二甲基-1H-吡咯-1-基]苯甲酸甲酯
英文别名
ML 397
VU0155094
VU0155094(ML-397)
VU0155094 (Synonyms: ML397)
Methyl 4-[3-[2-[[4-(acetylamino)phenyl]thio]acetyl]-2,5-dimethyl-1H-pyrrol-1-yl]benzoate
Benzoic acid, 4-[3-[2-[[4-(acetylamino)phenyl]thio]acetyl]-2,5-dimethyl-1H-pyrrol-1-yl]-, methyl ester

物理化学性质

沸点667.0±55.0 °C(Predicted)
密度1.21±0.1 g/cm3(Predicted)
酸度系数(pKa)14.56±0.70(Predicted)
形态Solid
颜色White to light yellow

应用领域

用途一
ML397, also known as VU0155094, is a positive allosteric modulator. ML397 showed differential activity at the various group III mGlus. Additionally, both compounds show probe dependence when assessed in the presence of distinct orthosteric agonists.
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