7414-56-4
中文名称
ADENYLYLMETHYLENEDIPHOSPHONATE SODIUM SALT
CAS
7414-56-4
分子式
C11H17N5NaO12P3
分子量
527.19
MOL 文件
7414-56-4.mol
7414-56-4 结构式
基本信息
中文别名
AMP-PCP DISODIUMΒ,Γ-亚甲基腺苷 5'-三磷酸 二钠盐
Β,Γ-METHYLENEADENOSINE 5′-TRIPHOSPHATE DISODIUM SALT
英文别名
AMP-PCP disodiumAMP-PCP SODIUM SALT
AMP-PCP disodium salt
β,γ-Methyleneadenosine 5′-triphosphate
ADENYLYLMETHYLENEDIPHOSPHONATE SODIUM SALT
Adenylylmethylenediphosphonate disodium salt
B-GAMMA-METHYLENEADENOSINE 5-*TRIPHOSPHA TE SODIUM
β,γ-Methyleneadenosine 5μ-triphosphate disodium salt
BETA,GAMMA-METHYLENEADENOSINE 5'-TRIPHOSPHATE SODIUM SALT
beta,gamma-Methyleneadenosine 5'-triphosphate disodium salt
ADENYLYLMETHYLENEDIPHOSPHONATE SODIUM SALT价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | HY-106723A | ADENYLYLMETHYLENEDIPHOSPHONATE SODIUM SALT AMP-PCP disodium | 7414-56-4 | 1mg | 600元 |
| 2024/04/30 | HY-106723A | ADENYLYLMETHYLENEDIPHOSPHONATE SODIUM SALT AMP-PCP disodium | 7414-56-4 | 5mg | 1400元 |
| 2024/04/30 | HY-106723A | ADENYLYLMETHYLENEDIPHOSPHONATE SODIUM SALT AMP-PCP disodium | 7414-56-4 | 10 mg | 2400元 |
常见问题列表
生物活性
AMP-PCP disodium 是一种 ATP 类似物，可以以 Kd 值 为 3.8 μM 来结合到 Hsp90 的 N 末端结构域。AMP-PCP disodium 结合有利于 Hsp90 活性同型二聚体的形成。靶点
|
HSP90 3.8 μM (Kd) |
体外研究
AMP-PCP binding favors the formation of the active homodimer of Hsp90 by enhancing the slow-motion featured conformational exchanges of those residues (A117-A141) within the lid segment (A111-G135) and around region. In total, 170 non-proline residues are identified for the triple-labeled Hsp90 bound with AMP-PCP.