76001-09-7

中文名称 3-[[2-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-2-oxoethyl]amino]benzamide

英文名称 3-[[2-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-2-oxoethyl]amino]benzamide

CAS 76001-09-7

分子式 C19H23N3O4

分子量 357.4

MOL 文件 76001-09-7.mol

76001-09-7 结构式

基本信息物理化学性质图谱信息常见问题列表

基本信息

中文别名

化合物 T10124
化合物ANTIULCER AGENT 1

英文别名

Antiulcer Agent 1
3-[[2-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-2-oxoethyl]amino]benzamide
Benzamide, 3-[[2-[[2-(3,4-dimethoxyphenyl)ethyl]amino]-2-oxoethyl]amino]-

物理化学性质

储存条件-20°C储存

溶解度溶于二甲基亚砜

图谱信息

3-[[2-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-2-oxoethyl]amino]benzamide(76001-09-7)核磁图(¹HNMR)

常见问题列表

生物活性

Antiulcer Agent 1 是 2-(3,4-dimethoxyphenyl)ethylamine 的衍生物，是一种口服剂，处于新药开发的探索阶段。

体内研究

The hydrochloride form shows incompatibility with the excipients used for oral dosage forms. There are several crystal forms of the free base, namely, alpha-anhydrate, beta-anhydrate, monohydrate, and trihydrate. The trihydrate form is unstable. The degree of crystallinity of the beta-anhydrate form is difficult to control. The monohydrate form is difficult to manufacture with constant quality. The serum levels of the compounds in rats are almost related to the dissolution rates in the JP 1st disintegration medium from the discs. The serum level of alpha-anhydrate is the lowest.