76788-83-5
76788-83-5 结构式
基本信息
英文别名
cloxacillin sulfone6α-[3-(2-Chlorophenyl)-5-methyl-4-isoxazolyl]penicillanic acid 4,4-dioxidesodium salt
应用领域
用途一
Cloxacillin sulfone is an antibiotic useful for the treatment of a number of bacterial infections. It is semisynthetic and in the same class as penicillin. Cloxacillin is used against staphylococci that produce beta-lactamase, due to its large R chain, which does not allow the beta-lactamases to bind. This drug has a weaker antibacterial activity than benzylpenicillin, and is devoid of serious toxicity except for allergic reactions. Cloxacillin was discovered and developed by Beecham. It is sold under a number of trade names, including Cloxapen, Cloxacap, Tegopen and Orbenin. It is on the World Health Organization's List of Essential Medicines, the most important medication needed in a basic health system.