851304-36-4
中文名称
化合物 T27760
英文名称
3-[(5Z)-5-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid
CAS
851304-36-4
分子式
C17H12N2O6S2
分子量
404.42
MOL 文件
851304-36-4.mol
851304-36-4 结构式
基本信息
中文别名
化合物 T27760 英文别名
KYA17973-[(5Z)-5-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid
应用领域
用途一
KYA1797 is a novel inhibitor of the Wnt/?-catenin pathway, binding directly to the regulators of G-protein signaling domain of axin, initiating ?-catenin and Ras degradation through enhancement of the ?-catenin destruction complex activating GSK3?, effectively suppressing the growth of CRCs harboring APC and KRAS mutations.