85392-79-6
85392-79-6 结构式
基本信息
中文别名
吲达尼定 英文别名
IndanidineIndanidinum
Unii-mp564ife34
Indanidine [inn]
4-(2-Imidazolin-2-ylamino)-2-methyl-2H-imidazole
N-(2-Imidazolin-2-yl)-2-methyl-2H-indazol-4-amine
2H-Imidazole, 4-(2-imidazolin-2-ylamino)-2-methyl-
N-(4,5-Dihydro-1H-imidazol-2-yl)-2-methyl-2H-indazol-4-amine
2H-Indazol-4-amine, N-(4,5-dihydro-1H-imidazol-2-yl)-2-methyl-
物理化学性质
沸点413.3±37.0 °C(Predicted)
密度1.40±0.1 g/cm3(Predicted)
储存条件-20°C储存
溶解度溶于二甲基亚砜
酸度系数(pKa)8.83±0.10(Predicted)
常见问题列表
生物活性
Indanidine 是一种 α-肾上腺素能激动剂。靶点
alpha-adrenergic
体内研究
The selective alpha 1-adrenoceptor agonist, Indanidine, also behaved as a partial agonist in the aorta and produced no significant contractions of the small mesenteric artery. Since Idazoxan and Indanidine have been reported to raise blood pressure in the pithed rat via an action at vascular alpha 1-adrenoceptors, these results call into question the reliability of the small mesenteric artery assay as a predictor for alpha 1-adrenoceptor-mediated pressor activity in vivo.