863239-61-6
中文名称
奥贝胆酸杂质9
英文名称
Tauro Obeticholic acid
CAS
863239-61-6
分子式
C28H49NO6S
分子量
527.76
MOL 文件
863239-61-6.mol
更新日期
2024/04/28 11:58:04
863239-61-6 结构式
基本信息
中文别名
牛磺-胆固醇牛磺酰奥贝胆酸
英文别名
Tauro Obeticholic acidObeticholic Acid Impurity 56
Tauro-Obeticholic Acid DISCONTINUED. Please see T009025.
Ethanesulfonic acid, 2-[[(3α,5β,6α,7α)-6-ethyl-3,7-dihydroxy-24-oxocholan-24-yl]amino]-
Obeticholic Acid Impurity 4/Tauro-Obeticholic Acid/2-((R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-Ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethane-1-sulfonic acid
所属类别
有机原料：羧酸类化合物及衍生物物理化学性质
密度1.177±0.06 g/cm3(Predicted)
储存条件Store at -20°C, protect from light, stored under nitrogen
溶解度DMSO: soluble; Methanol: soluble; Water: soluble
酸度系数(pKa)1.42±0.50(Predicted)
形态固体
颜色White to yellow
稳定性吸湿性
奥贝胆酸杂质9价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/11/08 | HY-135399 | 奥贝胆酸杂质9 Tauro-Obeticholic acid | 863239-61-6 | 1mg | 5500元 |
常见问题列表
生物活性
Tauro-Obeticholic acid 是牛磺酸的活性代谢物。Obeticholic Acid 是一种口服生物可利用的法尼样X受体 (FXR) 激动剂。体外研究
Obeticholic acid is conjugated with taurine in the liver to form Tauro-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate Tauro-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces.