87096-84-2
87096-84-2 结构式
基本信息
猪神经调节肽 B
NEUROMEDIN B肽
NEUROMEDIN B
GNLWATGHFM-NH2
Pig neuromedin B
NEUROMEDIN B ≥90%
Porcine neuromedin B
NEUROMEDIN BNEUROMED
NEUROMEDIN B, PORCINE
Neuromedin B, ≥90% (HPLC)
Neuromedin B (pig spinal cord)
物理化学性质
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | HY-P0241 | GLY-ASN-LEU-TRP-ALA-THR-GLY-HIS-PHE-MET-NH2 Neuromedin B | 87096-84-2 | 1mg | 800元 |
| 2024/04/30 | HY-P0241 | GLY-ASN-LEU-TRP-ALA-THR-GLY-HIS-PHE-MET-NH2 Neuromedin B | 87096-84-2 | 10mg | 5400元 |
| 2024/01/25 | HY-P0241 | GLY-ASN-LEU-TRP-ALA-THR-GLY-HIS-PHE-MET-NH2 Neuromedin B | 87096-84-2 | 5mg | 3100元 |
常见问题列表
|
Human Endogenous Metabolite
|
Potency to stimulate contraction of rat uterine smooth muscle, that is used as bioassay for isolation of Neuromedin B (NMB), is compared with Bombesin (BN). The relative potency, calculated on molar basis by taking BN as 100, is 48% for GRP and 4.9% for NMB. NMB also has contractile activity on rat stomach strip, but the potency (ratio of peptide concentration required to elicit 50% maximum response; EC 50 ) is only 5% of BN (EC 50 of BN/EC 50 of NMB) and about 10% of GRP (EC 50 of GRP/ EC 50 of NMB).
Potencies of NMB and GRP for smooth muscle contraction of fundus in wild-type and NMB-R-deficient mice with ED 50 of 14.4±2.3 (n=8) and 10.9±2.3 (n=8) in wild-type mice and NMB-R-deficient mice, respectively.