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877399-51-4

中文名称 克唑替尼中间体3
英文名称 (R)-tert-butyl 4-(4-(6-aMino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
CAS 877399-51-4
分子式 C26H30Cl2FN5O3
分子量 550.45
MOL 文件 877399-51-4.mol
更新日期 2024/10/26 08:59:49
877399-51-4 结构式 877399-51-4 结构式

基本信息

中文别名
克唑替尼中间体3
克尼唑替尼中间体
((R) - 叔丁基4-(4-(6-氨基-5-(1-(2,6-二氯-3-氟苯基)乙氧基)吡啶-3-基
4-[4-[6-氨基-5-[[?-1-(2,6-二氯-3-氟苯基)乙基]氧基]吡啶-3-基]吡唑-1-基]哌啶-1-羧酸叔丁酯
4-[4-[6-氨基-5-[[(R)-1-(2,6-二氯-3-氟苯基)乙基]氧基]吡啶-3-基]吡唑-1-基]哌啶-1-羧酸叔丁酯
(R)-4-(4-(6-氨基-5-(1-(2,6-二氯-3-氟苯基)乙氧基)吡啶-3-基)-1H-吡唑-1-基)哌啶-1-羧酸叔丁酯
((R)-叔丁基4-(4-(6-氨基-5-(1-(2,6-二氯-3-氟苯基)乙氧基)吡啶-3-基)-1H-吡唑-1-基]基)哌啶-1-羧酸叔丁酯)
英文别名
Crizotinib Impurity 23
(R)-tert-butyl 4-(4-(6-aMino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)
tert-butyl 4-[4-[6-amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-3-yl]pyrazol-1-yl]piperidine-1-carboxylate
tert-butyl 4-(4-(6-amino-5-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
tert-butyl (R)-4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
(R)-tert-butyl 4-(4-(6-aMino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
tert-butyl 4-[4-(6-amino-5-{[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethyl]oxy}-3-pyridinyl)-1H-pyrazol-1-yl]-1-piperidinecarboxylate
4-[4-[6-Amino-5-[[(R)-1-(2,6-dichloro-3-fluorophenyl)ethyl]oxy]pyridin-3-yl]pyrazol-1-yl]piperidine-1-carboxylic acid tert-butyl ester
1-Piperidinecarboxylic acid,4-[4-[6-aMino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-pyridinyl]-1H-pyrazol-1-yl]-, 1,1-diMethylethyl ester
(R)-tert-butyl 4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridine -3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate (R)-tert-butyl 4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridine -3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

物理化学性质

熔点150℃
沸点654.7±55.0 °C(Predicted)
密度1.38±0.1 g/cm3(Predicted)
储存条件Keep in dark place,Inert atmosphere,2-8°C
酸度系数(pKa)7.11±0.10(Predicted)

安全数据

危险性符号(GHS)GHS hazard pictograms
GHS07
警示词警告
危险性描述H302-H315-H319-H335
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