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94071-26-8

中文名称 SER-GLY-SER-ALA-LYS-VAL-ALA-PHE-SER-ALA-ILE-ARG-SER-THR-ASN-HIS: SGSAKVAFSAIRSTNH
英文名称 CEREBELLIN
CAS 94071-26-8
分子式 C69H113N23O23
分子量 1632.78
MOL 文件 94071-26-8.mol
更新日期 2024/07/14 14:44:31
94071-26-8 结构式 94071-26-8 结构式

基本信息

中文别名
小脑肽
英文别名
CEREBELLIN
Cerebellin (rat)
SGSAKVAFSAIRSTNH
SER-GLY-SER-ALA-LYS-VAL-ALA-PHE-SER-ALA-ILE-ARG-SER-THR-ASN-HIS
H-SER-GLY-SER-ALA-LYS-VAL-ALA-PHE-SER-ALA-ILE-ARG-SER-THR-ASN-HIS-OH
Nh2-Ser-Gly-Ser-Ala-Lys-Val-Ala-Phe-Ser-Ala-Ile-Arg-Ser-Thr-Asn-His-OH
Cerebellin H-Ser-Gly-Ser-Ala-Lys-Val-Ala-Phe-Ser-Ala-Ile-Arg-Ser-Thr-Asn-His-OH
SER-GLY-SER-ALA-LYS-VAL-ALA-PHE-SER-ALA-ILE-ARG-SER-THR-ASN-HIS: SGSAKVAFSAIRSTNH
L-Histidine, L-serylglycyl-L-seryl-L-alanyl-L-lysyl-L-valyl-L-alanyl-L-phenylalanyl-L-seryl-L-alanyl-L-isoleucyl-L-arginyl-L-seryl-L-threonyl-L-asparaginyl-

物理化学性质

储存条件-15°C
形态固体
颜色白色至灰白色
序列H-Ser-Gly-Ser-Ala-Lys-Val-Ala-Phe-Ser-Ala-Ile-Arg-Ser-Thr-Asn-His-OH
SER-GLY-SER-ALA-LYS-VAL-ALA-PHE-SER-ALA-ILE-ARG-SER-THR-ASN-HIS: SGSAKVAFSAIRSTNH价格(试剂级)
报价日期产品编号产品名称CAS号包装价格
2023/03/20HY-P1544SER-GLY-SER-ALA-LYS-VAL-ALA-PHE-SER-ALA-ILE-ARG-SER-THR-ASN-HIS: SGSAKVAFSAIRSTNH
Cerebellin
94071-26-81mg2200元
2023/03/20HY-P1544SER-GLY-SER-ALA-LYS-VAL-ALA-PHE-SER-ALA-ILE-ARG-SER-THR-ASN-HIS: SGSAKVAFSAIRSTNH
Cerebellin
94071-26-85mg6600元
2023/03/20HY-P1544SER-GLY-SER-ALA-LYS-VAL-ALA-PHE-SER-ALA-ILE-ARG-SER-THR-ASN-HIS: SGSAKVAFSAIRSTNH
Cerebellin
94071-26-810mg9900元

常见问题列表

生物活性
Cerebellin是广泛分布于中枢神经系统的神经调节肽。
体外研究

Cerebellin concentration-dependently (from 1 to 100 nM) increases norepinephrine (but not epinephrine) and cyclic-AMP production by adrenomedullary tissue in vitro .

体内研究

Cerebellin potently stimulates norepinephrine release by rat adrenal medulla, acting through adenylate-cyclase/PKA-coupled receptors, and enhances adrenocortical steroid secretion in vivo (i.e. when the integrity of adrenal gland is preserved) through an indirect paracrine mechanism involving the release of medullary catecholamines. Cerebellin reduces plasma insulin levels in rats after 1 and 2 h. Cerebellin decreases insulin secretion from isolated rat pancreatic islets at high (11 mM), but not at low (3.33 mM) glucose concentration. Cerebellin inhibits stimulated insulin secretion from clonal rat insulinoma (INS-1) cells, reduces forskolin-induced production of cAMP and intracellular calcium concentration.

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