96-88-8
中文名称
2-甲基-2,6-壬二烯-1-胺
英文名称
N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide
CAS
96-88-8
分子式
C15H22N2O
分子量
246.348
MOL 文件
96-88-8.mol
更新日期
2024/06/13 11:53:39
96-88-8 结构式
基本信息
中文别名
美哌卡因6-壬二烯-1-胺
2-甲基-2,6-壬二烯-1-胺
N-(26-二甲基苯基)-1-甲基哌啶-2-甲酰胺
英文别名
C07528Carbocain
Polocaine
Mepicaine
Carbocaine
Scandicain
Scandicaine
DL-Mepivacaine
1-Methyl-2',6'-pipecoloxylidide
Mepivacaine (base and/or unspecified salts)
所属类别
有机原料：氨基化合物物理化学性质
熔点150-151°
沸点389.35°C (rough estimate)
密度0.9978 (rough estimate)
折射率1.6280 (estimate)
储存条件-20°C储存
溶解度DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
酸度系数(pKa)14.85±0.70(Predicted)
形态结晶固体
颜色White to off-white
水溶解性2.217g/L(25 ºC)
2-甲基-2,6-壬二烯-1-胺价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | S5392 | 2-甲基-2,6-壬二烯-1-胺 Mepivacaine | 96-88-8 | 25mg | 794.84元 |
常见问题列表
生物活性
Mepivacaine 是一种酰胺型药剂，可暂时使局部失去知觉。Mepivacaine 与神经元细胞膜上特定的电压门控钠离子通道结合，抑制钠离子内流和膜去极化。体外研究
Mepivacaine binds to specific voltage-gated sodium ion channels in neuronal cell membranes, which inhibits both sodium influx and membrane depolarization. This leads to a blockage of nerve impulse initiation and conduction and results in a reversible loss of sensation. Compared to other local anesthetics, this agent has a more rapid onset and moderate duration of action.
Mepivacaine has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine).
Mepivacaine displays a preferential use-dependent block of Na(v)1.8, S(-)-bupivacaine displays a preference for TTXs Na(+) channels.