97559-35-8
中文名称
ASP-SER-PHE-VAL-GLY-LEU-MET-NH2
英文名称
NEUROKININ A (4-10)
CAS
97559-35-8
分子式
C34H54N8O10S
分子量
766.91
MOL 文件
97559-35-8.mol
更新日期
2024/09/10 09:46:35
97559-35-8 结构式
基本信息
中文别名
4-10-神经激肽 A 英文别名
NKA(4-10)DSFVGLM-NH2
NEUROKININ A (4-10)
A-NEUROKININ FRAGMENT 4-10
α-neurokinin fragment 4-10
Α-NEUROKININ FRAGMENT 4-10
ALPHA-NEUROKININ FRAGMENT 4-10
Α-NEUROKININ FRAGMENT 4-10 ≥97%
ASP-SER-PHE-VAL-GLY-LEU-MET-NH2
H-ASP-SER-PHE-VAL-GLY-LEU-MET-NH2
物理化学性质
沸点1231.2±65.0 °C(Predicted)
密度1.276±0.06 g/cm3(Predicted)
储存条件−20°C
酸度系数(pKa)3.69±0.10(Predicted)
形态固体
常见问题列表
生物活性
Neurokinin A (4-10) 是速激肽 NK2 受体激动剂。靶点
NK 2 receptor
体外研究
Neurokinin A (NKA) and its truncated form NKA(4-10) are potent spasmogens of human colon circular muscle, an action mediated exclusively via tachykinin NK 2 receptors. A structure-activity study of the neurokinin A (NKA) fragment NKA(4-10) is performed to investigate the importance of amino acid residues for receptor efficacy, potency and affinity at the NK 2 receptor in human colon circular muscle. A high density of NK 2 receptors has been demonstrated in this tissue, using in vitro autoradiography and radioligand binding.