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97627-24-2

中文名称 N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea
英文名称 N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea
CAS 97627-24-2
分子式 C13H12ClN3O
分子量 261.71
MOL 文件 97627-24-2.mol
97627-24-2 结构式 97627-24-2 结构式

基本信息

中文别名
化合物T12156
英文别名
Urea, N-(2-chloro-6-methylphenyl)-N'-4-pyridinyl-

物理化学性质

储存条件-20°C储存
溶解度溶于二甲基亚砜
形态Solid
颜色White to off-white

常见问题列表

生物活性
N-[(1R)-4-[(Aminoiminomethyl)amino]-1-[[[(1R)-1-(4-hydroxyphenyl)ethyl]amino]carbonyl]butyl]-α-phenylbenzeneacetamide 是一种抗惊厥剂,有研究广泛强直和部分性发作挛性的潜质。
体内研究

Compound shows anticonvulsant activity at 30 mg/kg in the initial tests with no signs of ataxia until 300 mg/kg. The activity seen with 30 mg/kg 37 is still present 4 h postdose. Compound is effective against seizures induced by maximal electroshock but does not protect mice from clonic seizures produced by the convulsant pentylenetetrazol. The overall pharmacological profile suggests that Compound would be of therapeutic use in the treatment of generalized tonic-clonic and partial seizures. Compound is selected for clinical trials.

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