98791-67-4
中文名称
BAY-K-8644 ((R)-(+)-);R-4407;NI-105;(+)-BAY-K-8644
英文名称
R(+)-BAY K 8644
CAS
98791-67-4
分子式
C16H15F3N2O4
分子量
356.3
MOL 文件
98791-67-4.mol
更新日期
2024/06/17 17:25:37
98791-67-4 结构式
基本信息
中文别名
钙离子通道抑制剂(BAY-K-8644 ((R)-(+)-)) 英文别名
R-4407NI 105
BAY-r-4407
BAY-k 4407
(+)-BAY-K-8644
R(+)-BAY K 8644
Bay-K-8644 ((R)-(+)-)
R(+)-BAY K 8644 98% 0 C
(+/-)-BAY K 8644, 0 TO 5 °C
(R)(+)BayK8644,(R) (+) Bay K 8644
BAY-K-8644 ((R)-(+)-);R-4407;NI-105;(+)-BAY-K-8644价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | HY-15125 | BAY-K-8644 ((R)-(+)-);R-4407;NI-105;(+)-BAY-K-8644 (R)-(+)-Bay-K-8644 | 98791-67-4 | 5mg | 1350元 |
| 2024/04/30 | HY-15125 | BAY-K-8644 ((R)-(+)-);R-4407;NI-105;(+)-BAY-K-8644 (R)-(+)-Bay-K-8644 | 98791-67-4 | 10mg | 1800元 |
| 2024/04/30 | HY-15125 | BAY-K-8644 ((R)-(+)-);R-4407;NI-105;(+)-BAY-K-8644 (R)-(+)-Bay-K-8644 | 98791-67-4 | 25mg | 4000元 |
常见问题列表
生物活性
(R)-(+)-Bay-K-8644 是钙离子通道抑制剂。(R)-(+)-Bay-K-8644 抑制 Ba2+电流 (IBa)，IC50 为 975 nM。靶点
IC50: 975 nM (I Ba )
体外研究
(R)-(+)-Bay-K-8644, a conventional racemic mixture of Bay K 8644, is widely used as an L-type Ca 2+ channel agonist. Each optical isomer possesses opposite effects on I Ba , (R)-(+)-Bay-K-8644 as an antagonist and S(-)-Bay K 8644 as an agonist. (R)-(+)-Bay-K-8644 inhibits Ba 2+ currents (I Ba ) (IC 50 =975 nM). When (R)-(+)-Bay-K-8644 (0.5 μM) is applied, I Ba is suppressed to 71±10% of control. In the presence of (R)-(+)-Bay-K-8644I Ba . (R)-(+)-Bay-K-8644 is a calcium channel inhibitor.