阿洛酮糖腺苷
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- CAS号:
- 1874-54-0
- 英文名:
- psicofuranine
- 英文别名:
- U-9586;NSC 53104;psicofuranin;psicofuranine;Angustmycin C;Psicofuranosyladenine;1'-(Hydroxymethyl)adenosine;Psicofuranine [AngustMycin C];9-beta-D-Psicofuranosyladenine;Adenosine, 1'-C-(hydroxymethyl)-
- 中文名:
- 阿洛酮糖腺苷
- 中文别名:
- 狭霉素C;阿洛酮糖腺苷;化合物 T16677
- CBNumber:
- CB01334610
- 分子式:
- C11H15N5O5
- 分子量:
- 297.27
- MOL File:
- 1874-54-0.mol
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阿洛酮糖腺苷化学性质
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熔点:
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212-214℃ (decomposition)
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比旋光度:
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D25 -68° (dimethylformamide)
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沸点:
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720.1±70.0 °C(Predicted)
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密度:
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2.02±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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形态:
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solid
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酸度系数(pKa):
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12.87±0.70(Predicted)
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颜色:
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White to off-white
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阿洛酮糖腺苷性质、用途与生产工艺
Psicofuramine 是一种核苷抗生素，具有抑制黄嘌呤 5'-磷酸氨化酶的作用。Psicofuramine 还可以特异性抑制 GMP 合酶，并中断寄生虫的生长。Psicofuramine 对恶性疟原虫的生长具有剂量依赖性抑制作用。
Xanthosine 5'-phosphate aminase
P. falciparum
E. coli
Psicofuranine specifically inhibits bacterial GMP synthase as demonstrated by isolation of Psicofuranine-resistant Escherichia coli mutants with mutations in the gene encoding GMP synthase and inhibition of bacterial growth. Psicofuranine exhibits a dose-dependent inhibition of
P. falciparum
growth with an
IC
50
of 0.3 mM. The Psicofuranine inhibitory concentration is similar to that of
E. coli
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阿洛酮糖腺苷
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-119819 | 阿洛酮糖腺苷
Psicofuranine | 1874-54-0 | 1mg | 2340元 |
1874-54-0, 阿洛酮糖腺苷 相关搜索:
- 化合物 T16677
- 狭霉素C
- 阿洛酮糖腺苷
- 1874-54-0
- Adenosine, 1'-C-(hydroxymethyl)-
- psicofuranin
- NSC 53104
- 9-beta-D-Psicofuranosyladenine
- 9-beta-D-Psicofuranosyl-6-aminopurine
- 1'-(Hydroxymethyl)adenosine
- Psicofuranine [AngustMycin C]
- U-9586
- Psicofuranosyladenine
- Angustmycin C
- 9-β-D-Psicofuranosyl-9H-purin-6-amine
- 9-(β-D-Psicofuranosyl)-9H-purin-6-amine
- psicofuranine