二氟比鲁卡胺
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- CAS号:
- 90357-05-4
- 英文名:
- Desfluoro Bicalutamide
- 英文别名:
- Bicalutamide-EP-Imp-A;Desfluoro Bicalutamide;Bicalutamide impurity B;Bicalutamide EP Impurity A;Bicalutamide Impurity 3(EP Impurity A);Bicalutamide Impurity 3(Bicalutamide EP Impurity A);Bicalutamide EP Impurity A (Desfluoro Bicalutamide);3-(benzenesulfonyl)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide;Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-3-(phenylsulfonyl)-;(+/-)-N-[4-Cyano-3-(trifluoroMethyl)phenyl]-2-hydroxy-2-Methyl-3-(phenylsulfonyl)propanaMide
- 中文名:
- 二氟比鲁卡胺
- 中文别名:
- 脱氟比卡鲁胺;去氟比卡鲁胺;二氟比鲁卡胺;去氟代比卡鲁胺;比卡鲁胺EP杂质A;比卡鲁胺杂质A(EP);比卡鲁胺EP杂质A(去氟比卡鲁胺);比卡鲁胺EP杂质A(脱氟比卡鲁胺);比卡鲁胺杂质3(比卡鲁胺EP杂质A);N-[4-氰基-3-(三氟甲基)苯基]-2-羟基-2-甲基-3-(苯磺酰基)丙酰胺
- CBNumber:
- CB02487014
- 分子式:
- C18H15F3N2O4S
- 分子量:
- 412.38
- MOL File:
- 90357-05-4.mol
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二氟比鲁卡胺化学性质
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熔点:
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175-178 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
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沸点:
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656.1±55.0 °C(Predicted)
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密度:
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1.48±0.1 g/cm3(Predicted)
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储存条件:
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Refrigerator
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溶解度:
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Chloroform (Sparingly, Sonicated), Methanol (Sparingly)
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形态:
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Solid
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酸度系数(pKa):
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11.22±0.29(Predicted)
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颜色:
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White to Off-White
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CAS 数据库:
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90357-05-4
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二氟比鲁卡胺性质、用途与生产工艺
二氟比鲁卡胺是比卡鲁胺EP杂质A。比卡鲁胺是由英国Astra Zeneca公司研发成功,1995年首次在英国上市。本药用于治疗前列腺癌,它是应用最为广泛的抗雄性激素药物。
二氟比鲁卡胺是比卡鲁胺EP杂质A。比卡鲁胺(Bicalutamide)作为非甾体抗雄性激素化合物,能反馈抑制垂体前叶分泌促性腺,可减少雄性激素的产生却几乎无雄性激素活性。
二氟比鲁卡胺
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90357-05-4, 二氟比鲁卡胺 相关搜索:
- Sulfur & Selenium Compounds
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Impurities
- Aromatics
- 杂质对照品
- 标准品
- 比卡鲁胺杂质3(比卡鲁胺EP杂质A)
- 比卡鲁胺EP杂质A(去氟比卡鲁胺)
- 比卡鲁胺EP杂质A(脱氟比卡鲁胺)
- 去氟比卡鲁胺
- 比卡鲁胺杂质A(EP)
- 比卡鲁胺EP杂质A
- N-[4-氰基-3-(三氟甲基)苯基]-2-羟基-2-甲基-3-(苯磺酰基)丙酰胺
- 二氟比鲁卡胺
- 去氟代比卡鲁胺
- 脱氟比卡鲁胺
- 90357-05-4
- Bicalutamide Impurity AQ: What is
Bicalutamide Impurity A Q: What is the CAS Number of
Bicalutamide Impurity A Q: What is the storage condition of
Bicalutamide Impurity A Q: What are the applications of
Bicalutamide Impurity A
- Bicalutamide Impurity 3(Bicalutamide EP Impurity A)
- Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-3-(phenylsulfonyl)-
- Bicalutamide Impurity 3(EP Impurity A)
- Bicalutamide impurity B
- 3-(benzenesulfonyl)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
- Bicalutamide EP Impurity A (Desfluoro Bicalutamide)
- Bicalutamide-EP-Imp-A
- (+/-)-N-[4-Cyano-3-(trifluoroMethyl)phenyl]-2-hydroxy-2-Methyl-3-(phenylsulfonyl)propanaMide
- Bicalutamide EP Impurity A
- Desfluoro Bicalutamide