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Brain Natriuretic Peptide (1-32), rat acetate
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- CAS号:
- 英文名:
- Brain Natriuretic Peptide (1-32), rat acetate
- 英文别名:
- Brain Natriuretic Peptide (1-32), rat acetate
- 中文名:
- 中文别名:
- CBNumber:
- CB08202961
- 分子式:
- 分子量:
- 0
- MOL File:
- Mol file
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Brain Natriuretic Peptide (1-32), rat acetate化学性质
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形态:
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Solid
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颜色:
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White to off-white
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Brain Natriuretic Peptide (1-32), rat acetate性质、用途与生产工艺
Brain Natriuretic Peptide (1-32), rat acetate (BNP (1-32), rat acetate) 是一种含有 32 个氨基酸的多肽。可作为心力衰竭病人病残率和死亡率的生化标志。
B-type natriuretic peptide (BNP) combats cardiac stress by reducing blood pressure and ventricular fibrosis. Rat BNP BNP (1-32) (rBNP (1-32)) is an amino-truncated form of the 45 residue natural rat form of BNP. Atrial natriuretic peptide-(1-28) (ANP), brain natriuretic peptide-(1-32) (BNP) and C-Type natriuretic polypeptide (CNP) occur in the brain, are concentrated in the anteroventral area of the third cerebral ventricle and participate in the regulation of body fluid homeostasis. The ANP(1-28), BNP (1-32) and CNP(1-32) function in the mammalian brain to regulate salt and water homeostasis via their receptors NPR-A and NPR-B.
The depressor, natriuretic and cyclic GMP responses to several species of brain natriuretic peptide (BNP) are compared to atrial natriureticpeptide (ANP) 99-126 in conscious spontaneously hypertensive rats (SHR) and in conscious cynomolgus monkeys treated with vehicle or the selective neutral endopeptidase inhibitor SQ 28603. In the conscious SHR, the natriuretic and cyclic GMP responses to 3 nmol/kg i.v. rat BNP (1-32) greater than rat ANP 99-126 greater than pig BNP-26 and sre significantly potentiated by 100 mumol/kg i.v. SQ 28,603. Human BNP-32 is inactive in the SHR treated with either vehicle or SQ 28,603. In contrast, 1 nmol/kg i.v. of human BNP (1-32) stimulates renal and depressor responses in the conscious monkeys that are greater than or equal to those elicited by human ANP 99-126, whereas 3 nmol/kg i.v. rat BNP (1-32) reduces mean arterial pressure without affecting renal function.
Brain Natriuretic Peptide (1-32), rat acetate
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Brain Natriuretic Peptide (1-32), rat acetate 试剂级价格
更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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2024/08/19 | HY-P1519B | Brain Natriuretic Peptide (1-32), rat acetate | | 1mg | 4000元 |
2024/08/19 | HY-P1519B | Brain Natriuretic Peptide (1-32), rat acetate | | 5mg | 10000元 |
Brain Natriuretic Peptide (1-32), rat acetate
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