伊曲茶碱杂质
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- CAS号:
- 160434-48-0
- 英文名:
- 4-DesMethyl Istradefylline
- 英文别名:
- Itraphylline impurities6;4-Desmethyl Istradefylline;Istradefylline Impurity 14;Itraphylline impurities869;Istradefylline M1 metabolite;4-DesMethyl Istradefylline impurity;Istradefylline 4-O-Desmethyl Impurity;(E)-1,3-diethyl-8-(4-hydroxy-3-methoxystyryl)-7-methyl-1H-purine-2,6(3H,7H)-dione;1H-Purine-2,6-dione, 1,3-diethyl-3,7-dihydro-8-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-7-methyl-, (E)- (9CI)
- 中文名:
- 伊曲茶碱杂质
- 中文别名:
- 4-去甲基异氟烷;伊曲茶碱杂质14;伊曲茶碱杂质869;4-去甲基伊曲茶碱
- CBNumber:
- CB12695351
- 分子式:
- C19H22N4O4
- 分子量:
- 370.4
- MOL File:
- 160434-48-0.mol
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伊曲茶碱杂质化学性质
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沸点:
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604.8±65.0 °C(Predicted)
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密度:
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1.30±0.1 g/cm3(Predicted)
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酸度系数(pKa):
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9.88±0.31(Predicted)
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伊曲茶碱杂质性质、用途与生产工艺
4-Desmethyl Istradefylline 是 Istradefylline 的代谢物。Istradefylline 是一种有效的，选择性的，可口服的 adenosine A2A receptor 拮抗剂，在帕金森疾病模型试验中，Ki 值为 2.2 nM。
用途
4-Desmethyl Istradefylline is an impurity of Istradefylline (I927000), a selective A(2A) antagonist used in the treatment of Parkinson鈥檚 disease. 4-Desmethyl Istradefylline have also been shown to exh
ibit inhibitory potency towards adenosine A2A receptors and is classified as its an adenosine A2A receptor antagonist.
伊曲茶碱杂质
上下游产品信息
上游原料
下游产品
160434-48-0, 伊曲茶碱杂质 相关搜索:
- Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
- 杂质对照品
- 伊曲茶碱杂质869
- 4-去甲基异氟烷
- 4-去甲基伊曲茶碱
- 伊曲茶碱杂质14
- 160434-48-0
- 4-Desmethyl Istradefylline
- Itraphylline impurities6
- Itraphylline impurities869
- Istradefylline M1 metabolite
- Istradefylline 4-O-Desmethyl Impurity
- 1H-Purine-2,6-dione, 1,3-diethyl-3,7-dihydro-8-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-7-methyl-, (E)- (9CI)
- Istradefylline Impurity 14
- 4-DesMethyl Istradefylline impurity
- (E)-1,3-diethyl-8-(4-hydroxy-3-methoxystyryl)-7-methyl-1H-purine-2,6(3H,7H)-dione