PROPARGYL-PEG1-SS-PEG1-T-BUTYL ESTER
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- CAS号:
- 1807518-78-0
- 英文名:
- Propargyl-PEG1-SS-PEG1-t-butyl ester
- 英文别名:
- Propargyl-PEG1-SS-PEG1-C2-Boc;Propargyl-PEG1-SS-PEG1-t-butyl ester;Propanoic acid, 3-[2-[[2-(2-propyn-1-yloxy)ethyl]dithio]ethoxy]-, 1,1-dimethylethyl ester
- 中文名:
- PROPARGYL-PEG1-SS-PEG1-T-BUTYL ESTER
- 中文别名:
- 丙炔-单乙二醇-二硫键-单乙二醇-叔丁酯;丙炔基-聚乙二醇-二硫键-聚乙二醇-叔丁酯
- CBNumber:
- CB13062615
- 分子式:
- C14H24O4S2
- 分子量:
- 320.47
- MOL File:
- 1807518-78-0.mol
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PROPARGYL-PEG1-SS-PEG1-T-BUTYL ESTER化学性质
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沸点:
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407.4±40.0 °C(Predicted)
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密度:
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1.114±0.06 g/cm3(Predicted)
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形态:
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Liquid
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颜色:
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Colorless to light yellow
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PROPARGYL-PEG1-SS-PEG1-T-BUTYL ESTER性质、用途与生产工艺
Propargyl-PEG1-SS-PEG1-C2-Boc 是一种 PROTAC 连接桥，属于 Alkyl/ether 类。Propargyl-PEG1-SS-PEG1-C2-Boc 可用于合成一系列 PROTAC 分子。Propargyl-PEG1-SS-PEG1-C2-Boc 是一种可降解 (cleavable) 的 ADC 连接桥，用于抗体药物结合物 (ADCs) 的合成。
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROPARGYL-PEG1-SS-PEG1-T-BUTYL ESTER
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1807518-78-0, PROPARGYL-PEG1-SS-PEG1-T-BUTYL ESTER 相关搜索:
- 丙炔基-聚乙二醇-二硫键-聚乙二醇-叔丁酯
- 丙炔-单乙二醇-二硫键-单乙二醇-叔丁酯
- 1807518-78-0
- Propanoic acid, 3-[2-[[2-(2-propyn-1-yloxy)ethyl]dithio]ethoxy]-, 1,1-dimethylethyl ester
- Propargyl-PEG1-SS-PEG1-C2-Boc
- Propargyl-PEG1-SS-PEG1-t-butyl ester