ADAMTS-5
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- CAS号:
- 929634-33-3
- 英文名:
- ADAMTS-5
- 英文别名:
- ADAMTS-5 Inhibitor;ADAMTS-5 inhibitor - Compound 12;ADAMTS5 Inhibitor,ADAMTS 5 Inhibitor;5-((5-((4-Chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one;4-Thiazolidinone, 5-[[5-[[(4-chlorophenyl)methyl]thio]-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methylene]-2-thioxo-;(5Z)-5-[[5-[(4-chlorophenyl)methylsulfanyl]-1-methyl-3-(trifluoromethyl)pyrazol-4-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
- 中文名:
- ADAMTS-5
- 中文别名:
- 化合物 T14124;ADAMTS-5抑制剂;化合物ADAMTS-5 INHIBITOR;5-((5-((4-氯苄基)硫基)-1-甲基-3-(三氟甲基)-1H-吡唑-4-基)亚甲基)-2-硫代噻唑烷-4-酮
- CBNumber:
- CB13124308
- 分子式:
- C16H11ClF3N3OS3
- 分子量:
- 449.92
- MOL File:
- 929634-33-3.mol
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ADAMTS-5化学性质
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密度:
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1.59±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml
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形态:
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A crystalline solid
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酸度系数(pKa):
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6.69±0.50(Predicted)
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颜色:
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Light yellow to yellow
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ADAMTS-5性质、用途与生产工艺
ADAMTS-5 Inhibitor 是一种有效的 ADAMTS-5 (aggrecanase-2) 抑制剂,IC50为 1.1 μM。ADAMTS-5 Inhibitor 的功能选择性比 ADAMTS-4 (aggrecanase-2) 高出 40 倍以上。
ADAMTS-5 (aggrecanase-2) is an extracellular matrix-degrading protease implicated in cartilage destruction in arthritis.
ADAMTS-5
上下游产品信息
上游原料
下游产品
更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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2024/08/19 | HY-114996 | ADAMTS-5 Inhibitor | | 1 mg | 772元 |
2024/08/19 | HY-114996 | ADAMTS-5 ADAMTS-5 Inhibitor | 929634-33-3 | 5mg | 1700元 |
929634-33-3, ADAMTS-5 相关搜索:
- 药靶配体
- C16H11ClF3N3OS3
- 5-((5-((4-氯苄基)硫基)-1-甲基-3-(三氟甲基)-1H-吡唑-4-基)亚甲基)-2-硫代噻唑烷-4-酮
- 化合物ADAMTS-5 INHIBITOR
- ADAMTS-5抑制剂
- 化合物 T14124
- 929634-33-3
- 5-((5-((4-Chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one
- ADAMTS5 Inhibitor,ADAMTS 5 Inhibitor
- ADAMTS-5 Inhibitor
- 4-Thiazolidinone, 5-[[5-[[(4-chlorophenyl)methyl]thio]-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methylene]-2-thioxo-
- ADAMTS-5 inhibitor - Compound 12
- (5Z)-5-[[5-[(4-chlorophenyl)methylsulfanyl]-1-methyl-3-(trifluoromethyl)pyrazol-4-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one