PC-马来酰亚胺-琥珀酰亚胺酯
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- CAS号:
- 1408057-91-9
- 英文名:
- PC Mal-NHS carbonate ester
- 英文别名:
- PC Mal-NHS carbonate ester;1-[4-[4-[[2-(2,5-Dioxo-2,5-dihydro-1-pyrrolyl)ethyl]amino]-4-oxobutoxy]-5-methoxy-2-nitrophenyl]ethyl (2,5-Dioxo-1-pyrrolidinyl) Carbonate;1-(4-(4-((2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)amino)-4-oxobutoxy)-5-methoxy-2-nitrophenyl)ethyl (2,5-dioxopyrrolidin-1-yl) carbonate;Carbonic acid, 1-[4-[4-[[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]amino]-4-oxobutoxy]-5-methoxy-2-nitrophenyl]ethyl 2,5-dioxo-1-pyrrolidinyl ester
- 中文名:
- PC-马来酰亚胺-琥珀酰亚胺酯
- 中文别名:
- PC 马来酰亚胺-活性碳酸酯;PC-马来酰亚胺-琥珀酰亚胺酯;碳酸[1-[4-[4-[[2-(2,5-二氧代-2,5-二氢-1-吡咯基)乙基]氨基]-4-氧代丁氧基]-5-甲氧基-2-硝基苯基]乙基(]酯[2,5-二氧代-1-吡咯烷基)]酯
- CBNumber:
- CB13373748
- 分子式:
- C24H26N4O12
- 分子量:
- 562.48
- MOL File:
- 1408057-91-9.mol
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PC-马来酰亚胺-琥珀酰亚胺酯化学性质
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密度:
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1.49±0.1 g/cm3(Predicted)
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溶解度:
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Soluble in DMSO, DCM, DMF
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酸度系数(pKa):
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15.25±0.46(Predicted)
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形态:
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Solid
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颜色:
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White to off-white
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PC-马来酰亚胺-琥珀酰亚胺酯性质、用途与生产工艺
PC Mal-NHS carbonate ester 是一种可降解 (cleavable) 的 ADC linker，可用于合成抗体偶联药物 (ADC)。
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PC-马来酰亚胺-琥珀酰亚胺酯
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1408057-91-9, PC-马来酰亚胺-琥珀酰亚胺酯 相关搜索:
- C24H26N4O12
- PC 马来酰亚胺-活性碳酸酯
- 碳酸[1-[4-[4-[[2-(2,5-二氧代-2,5-二氢-1-吡咯基)乙基]氨基]-4-氧代丁氧基]-5-甲氧基-2-硝基苯基]乙基(]酯[2,5-二氧代-1-吡咯烷基)]酯
- PC-马来酰亚胺-琥珀酰亚胺酯
- 1408057-91-9
- 1-[4-[4-[[2-(2,5-Dioxo-2,5-dihydro-1-pyrrolyl)ethyl]amino]-4-oxobutoxy]-5-methoxy-2-nitrophenyl]ethyl (2,5-Dioxo-1-pyrrolidinyl) Carbonate
- 1-(4-(4-((2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)amino)-4-oxobutoxy)-5-methoxy-2-nitrophenyl)ethyl (2,5-dioxopyrrolidin-1-yl) carbonate
- Carbonic acid, 1-[4-[4-[[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]amino]-4-oxobutoxy]-5-methoxy-2-nitrophenyl]ethyl 2,5-dioxo-1-pyrrolidinyl ester
- PC Mal-NHS carbonate ester