hDHODH-IN-1
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- CAS号:
- 1173715-42-8
- 英文名:
- hDHODH-IN-1
- 英文别名:
- hDHODH-IN-1;2-Butenamide, N-[1,1'-biphenyl]-4-yl-2-cyano-3-hydroxy-;N-([1,1'-Biphenyl]-4-yl)-2-cyano-3-hydroxybut-2-enamide;N-([1,1'-Biphenyl]-4-yl)-2-cyano-3-hydroxybut-2-enamide;hDHODH,proliferating-cell,Inhibitor,DNA/RNA Synthesis,dihydroorotate,anti-inflammatory,inhibit,hDHODH IN 1,dehydrogenase,LDH,human,Lactate Dehydrogenase,hDHODHIN1
- 中文名:
- hDHODH-IN-1
- 中文别名:
- 化合物 T11546;化合物HDHODH-IN-1;N-([1,1'-联苯]-4-基)-2-氰基-3-羟基丁-2-烯酰胺;N-([1,1'-联苯]-4-基)-2-氰基-3-羟基丁-2-烯酰胺
- CBNumber:
- CB15855428
- 分子式:
- C17H14N2O2
- 分子量:
- 278.31
- MOL File:
- 1173715-42-8.mol
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hDHODH-IN-1化学性质
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熔点:
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270-275 °C (decomp)
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沸点:
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514.6±50.0 °C(Predicted)
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密度:
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1.256±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO: 250 mg/mL (898.28 mM)
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酸度系数(pKa):
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5.20±0.50(Predicted)
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形态:
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Solid
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颜色:
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Off-white to light yellow
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hDHODH-IN-1性质、用途与生产工艺
hDHODH-IN-1 是一种人二氢乳清酸脱氢酶 (hDHODH) 抑制剂, 具有抗炎作用。
Human dihydroorotate dehydrogenase (hDHODH) is a class-2 dihydroorotate dehydrogenase. Because DHODH is required to ensure proliferating-cell viability, inhibitors have been developed to eliminate human DHODH (hDHODH) activity, which is associated with cancers, multiple sclerosis, and autoimmune and inflammatory diseases.
hDHODH-IN-1
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上游原料
下游产品
更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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2024/08/19 | HY-135658 | hDHODH-IN-1 hDHODH-IN-1 | 1173715-42-8 | 5 mg | 2000元 |
2024/08/19 | HY-135658 | hDHODH-IN-1 hDHODH-IN-1 | 1173715-42-8 | 10mM * 1mLin DMSO | 2200元 |
1173715-42-8, hDHODH-IN-1 相关搜索:
- 药靶配体
- N-([1,1'-联苯]-4-基)-2-氰基-3-羟基丁-2-烯酰胺
- N-([1,1'-联苯]-4-基)-2-氰基-3-羟基丁-2-烯酰胺
- 化合物HDHODH-IN-1
- 化合物 T11546
- 1173715-42-8
- N-([1,1'-Biphenyl]-4-yl)-2-cyano-3-hydroxybut-2-enamide
- N-([1,1'-Biphenyl]-4-yl)-2-cyano-3-hydroxybut-2-enamide
- hDHODH,proliferating-cell,Inhibitor,DNA/RNA Synthesis,dihydroorotate,anti-inflammatory,inhibit,hDHODH IN 1,dehydrogenase,LDH,human,Lactate Dehydrogenase,hDHODHIN1
- 2-Butenamide, N-[1,1'-biphenyl]-4-yl-2-cyano-3-hydroxy-
- hDHODH-IN-1