SAREDUTANT
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- CAS号:
- 142001-63-6
- 英文名:
- Saredutant
- 英文别名:
- SR 48968;Sr 48968c;(S)-N-Methyl-N(4-(4-acetylamino-4-phenylpiperidino)-2-(3,4-dichlorophenyl)butyl)benzamide;Benzamide, N-((2S)-4-(4-(acetylamino)-4-phenyl-1-piperidinyl)-2-(3,4-dichlorophenyl)butyl)-N-methyl-;Benzamide, N-(4-(4-(acetylamino)-4-phenyl-1-piperidinyl)-2-(3,4-dichlorophenyl)butyl)-N-methyl-, (S)-
- 中文名:
- SAREDUTANT
- 中文别名:
- 化合物 T16842
- CBNumber:
- CB21179709
- 分子式:
- C31H35Cl2N3O2
- 分子量:
- 552.53
- MOL File:
- 142001-63-6.mol
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SAREDUTANT化学性质
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沸点:
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734.7±60.0 °C(Predicted)
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密度:
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1.26±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO: 250 mg/mL (452.46 mM)
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酸度系数(pKa):
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15.88±0.20(Predicted)
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形态:
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Solid
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颜色:
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White to off-white
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SAREDUTANT性质、用途与生产工艺
Saredutant 是一种选择性 NK2 受体拮抗剂。
Saredutant, an NK2 receptor antagonist, has both antidepressant-like effects and synergizes with desipramine in an animal model of depression. Saredutant has dose-dependent effects on swim test immobility, with the low dose of 1 mg/kg having no effect and the doses of 3 and 10 mg/kg significantly reducing immobility.
SAREDUTANT
上下游产品信息
上游原料
下游产品
142001-63-6, SAREDUTANT 相关搜索:
- 化合物 T16842
- 142001-63-6
- Sr 48968c
- Benzamide, N-(4-(4-(acetylamino)-4-phenyl-1-piperidinyl)-2-(3,4-dichlorophenyl)butyl)-N-methyl-, (S)-
- Benzamide, N-((2S)-4-(4-(acetylamino)-4-phenyl-1-piperidinyl)-2-(3,4-dichlorophenyl)butyl)-N-methyl-
- (S)-N-Methyl-N(4-(4-acetylamino-4-phenylpiperidino)-2-(3,4-dichlorophenyl)butyl)benzamide
- SR 48968