PANCREATIC POLYPEPTIDE (BOVINE)
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- CAS号:
- 179986-89-1
- 英文名:
- PANCREATIC POLYPEPTIDE (BOVINE)
- 英文别名:
- PANCREATIC POLYPEPTIDE (BOVINE);Pancreatic polypeptide (pig),6-L-glutamic acid-;H-Ala-Pro-Leu-Glu-Pro-Glu-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Gln-Tyr-Ala-Ala-Glu-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Leu-Thr-Arg-Pro-Arg-Tyr-NH2
- 中文名:
- PANCREATIC POLYPEPTIDE (BOVINE)
- 中文别名:
- 胰腺多肽,牛
- CBNumber:
- CB2160531
- 分子式:
- 分子量:
- 0
- MOL File:
- Mol file
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PANCREATIC POLYPEPTIDE (BOVINE)化学性质
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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PANCREATIC POLYPEPTIDE (BOVINE)性质、用途与生产工艺
Pancreatic Polypeptide, bovine 是由 36 个氨基酸组成的直链多肽,由胰腺中产生,能够抑制由分泌素和胆囊素诱导的胰腺分泌。Pancreatic Polypeptide, bovine 是神经肽 (NPY) 受体激动剂,对 NPYR4 有很高的亲和性。
Pancreatic Polypeptide, bovine is an agonist of NPY receptor, with high affinity at NPYR4. Pancreatic Polypeptide (1 μM) does not alter proliferation in BRIN BD11 or 1.1B4 beta-cells, but reverses the decreased cell viability in BRIN BD11 cells induced by streptozotocin. Pancreatic Polypeptide (0.1 nM-1 μM) shows no effect on insulin secretion from isolated mouse islets, and does not affect the membrane potential and (Ca
2+
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i
levels in BRIN BD11 cells at 1 μM. Pancreatic Polypeptide, bovine inhibits secretin- and cholecystokinin-stimulated pancreatic secretion.
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I-Pancreatic Polypeptide, bovine shows no specific binding to pancreatic acini.
Pancreatic Polypeptide (25 nmol/kg bw, i.p.) reduces glucose-stimulated insulin concentrations but shows no effect on acute feeding behaviour in overnight fasted mice. Pancreatic Polypeptide, bovine (BPP; 40 μg/kg) inhibits CCK-33-induced pancreatic protein output during the entire bovine Pancreatic Polypeptide infusion period, but shows no effect on biliary protein output during CCK-33 or CCK-8 infusion.
PANCREATIC POLYPEPTIDE (BOVINE)
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PANCREATIC POLYPEPTIDE (BOVINE)
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179986-89-1, PANCREATIC POLYPEPTIDE (BOVINE) 相关搜索:
- peptide
- 目录肽
- 标准品
- 多肽
- Natriuretic Peptides
- Peptides
- BioChemical
- Amino Acids and Peptides
- Biochemicals and Reagents
- 胰腺多肽,牛
- 179986-89-1
- Pancreatic polypeptide (pig),6-L-glutamic acid-
- PANCREATIC POLYPEPTIDE (BOVINE)
- H-Ala-Pro-Leu-Glu-Pro-Glu-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Gln-Tyr-Ala-Ala-Glu-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Leu-Thr-Arg-Pro-Arg-Tyr-NH2