ARG14,LYS15]NOCICEPTIN
|
|
|
- CAS号:
- 236098-40-1
- 英文名:
- PHE-GLY-GLY-PHE-THR-GLY-ALA-ARG-LYS-SER-ALA-ARG-LYS-ARG-LYS-ASN-GLN
- 英文别名:
- [ARG14,LYS15]NOCICEPTIN;[ARG14,LYS15] ORPHANIN FQ;[ARG14, LYS15]NOCICEPTIN/ORPHANIN FQ;PHE-GLY-GLY-PHE-THR-GLY-ALA-ARG-LYS-SER-ALA-ARG-LYS-ARG-LYS-ASN-GLN;L-Glutamine, L-phenylalanylglycylglycyl-L-phenylalanyl-L-threonylglycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-arginyl-L-lysyl-L-asparaginyl-
- 中文名:
- ARG14,LYS15]NOCICEPTIN
- 中文别名:
- CBNumber:
- CB2210515
- 分子式:
- C82H137N31O22
- 分子量:
- 1909.16
- MOL File:
- 236098-40-1.mol
|
|
|
ARG14,LYS15]NOCICEPTIN化学性质
-
储存条件:
-
2-8°C
-
|
-
形态:
-
solid
-
|
-
颜色:
-
white
-
|
-
水溶解性:
-
Soluble to 1 mg/ml in water
-
|
ARG14,LYS15]NOCICEPTIN性质、用途与生产工艺
[Arg14,Lys15]Nociceptin 是一种高效、选择性的 NOP (ORL1; OP4) 受体激动剂，EC50为 1 nM。[Arg14,Lys15]Nociceptin 对阿片受体具有较高的选择性，对 NOP、μ、δ 和 κ 受体的 IC50 值分别为 0.32、280、>10000 和 1500 nM。
[Arg14,Lys15]Nociceptin is about 30-fold more potent than Nociceptin (NC) and produces longer lasting effects.
In in vivo experiments, [Arg14,Lys15]Nociceptin mimics the effects of NC, producing, after intracerebroventricular administration, pronociceptive effects in the tail-withdrawal assay and inhibiting the locomotor activity of the mice.
ARG14,LYS15]NOCICEPTIN
上下游产品信息
上游原料
下游产品
ARG14,LYS15]NOCICEPTIN
生产厂家
236098-40-1, ARG14,LYS15]NOCICEPTIN 相关搜索:
- Opioid receptor and opioid-like receptor
- C82H137N31O22
- 236098-40-1
- L-Glutamine, L-phenylalanylglycylglycyl-L-phenylalanyl-L-threonylglycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-arginyl-L-lysyl-L-asparaginyl-
- PHE-GLY-GLY-PHE-THR-GLY-ALA-ARG-LYS-SER-ALA-ARG-LYS-ARG-LYS-ASN-GLN
- [ARG14,LYS15] ORPHANIN FQ
- [ARG14, LYS15]NOCICEPTIN/ORPHANIN FQ
- [ARG14,LYS15]NOCICEPTIN