Necrosis Inhibitor, IM-54
|
|
|
- CAS号:
- 861891-50-1
- 英文名:
- Necrosis Inhibitor, IM-54
- 英文别名:
- IM-54;Necrosis Inhibitor, IM-54;2-(1H-Indol-3-yl)-3-pentylamino-maleimide;IM 54 (2-(1H-Indol-3-yl)-3-pentylamino-maleimide);Necrosis Inhibitor, IM-54 - CAS 861891-50-1 - Calbiochem;1-methyl-3-(1-methylindol-3-yl)-4-(pentylamino)pyrrole-2,5-dione;1-Methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 1-methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-;1-Methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione , IM-54
- 中文名:
- Necrosis Inhibitor, IM-54
- 中文别名:
- 化合物IM-54;化合物 T24160;坏死抑制剂,IM-54;IM 54(2-(1H-吲哚-3-基)-3-戊基氨基马来酰亚胺);1-甲基-3-(1-甲基-1H-吲哚-3-基)-4-(戊基氨基)-1H-吡咯-2,5-二酮
- CBNumber:
- CB22514666
- 分子式:
- C19H23N3O2
- 分子量:
- 325.4
- MOL File:
- 861891-50-1.mol
|
|
|
Necrosis Inhibitor, IM-54化学性质
-
沸点:
-
511.5±50.0 °C(Predicted)
-
|
-
密度:
-
1.20±0.1 g/cm3(Predicted)
-
|
-
储存条件:
-
2-8°C
-
|
-
溶解度:
-
DMSO: soluble5mg/mL (clear solution)
-
|
-
形态:
-
Yellow orange solid
-
|
-
酸度系数(pKa):
-
1.96±0.20(Predicted)
-
|
-
颜色:
-
light orange to dark orange
-
|
Necrosis Inhibitor, IM-54性质、用途与生产工艺
IM-54 是一种选择性的氧化应激诱导的坏死 (necrosis) 抑制剂。IM-54 对 H2O2 诱导的坏死有强烈的抑制作用。IM-54 是一种潜在的心脏保护剂和研究细胞死亡分子机制的生物工具。
IM-54 selectively inhibits oxidative stress-induced necrosis, but it does not inhibit apoptosis induced by various anticancer drugs or Fas ligand, or necroptosis.
IM-54 shows strong inhibition of H
2
O
2
-induced necrosis, with an IC
50
of 0.25 μM against HL-60 cells treated with H
2
O
2
.
Necrosis Inhibitor, IM-54
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/11/08 | HY-108351 | IM-54 | | 1 mg | 727元 |
| 2024/11/08 | HY-108351 | Necrosis Inhibitor, IM-54
IM-54 | 861891-50-1 | 5mg | 1600元 |
Necrosis Inhibitor, IM-54
生产厂家
861891-50-1, Necrosis Inhibitor, IM-54 相关搜索:
- Apoptosis Inhibitors
- 抑制剂
- 高端化学
- 86189-50-1
- IM 54(2-(1H-吲哚-3-基)-3-戊基氨基马来酰亚胺)
- 坏死抑制剂,IM-54
- 1-甲基-3-(1-甲基-1H-吲哚-3-基)-4-(戊基氨基)-1H-吡咯-2,5-二酮
- 化合物IM-54
- 化合物 T24160
- 861891-50-1
- 1-Methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione , IM-54
- 1H-Pyrrole-2,5-dione, 1-methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-
- Necrosis Inhibitor, IM-54 - CAS 861891-50-1 - Calbiochem
- IM 54 (2-(1H-Indol-3-yl)-3-pentylamino-maleimide)
- 1-methyl-3-(1-methylindol-3-yl)-4-(pentylamino)pyrrole-2,5-dione
- 2-(1H-Indol-3-yl)-3-pentylamino-maleimide
- 1-Methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione
- IM-54
- Necrosis Inhibitor, IM-54