恩曲他滨S-氧化物(非对映体混合物)
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- CAS号:
- 152128-77-3
- 英文名:
- (-)-EMtricitabine S-Oxide
(Mixture of DiastereoMers)
- 英文别名:
- EMtricitabine S-Oxide;Emtricitabine Impurity;Emtricitabine Sulfoxide;Emtricitabine Sulphoxide;Emtricitabine Impurity 2;Emtricitabine IP Impurity G;Emtricitabine Degradant-III;Emtricitabine IP Impurity H;Emtricitabine S-oxide(Mixture);Emtricitabine Sulfoxide Impurity
- 中文名:
- 恩曲他滨S-氧化物(非对映体混合物)
- 中文别名:
- 恩曲他滨亚砜;恩曲他滨杂质II;恩曲他滨 S-氧化物;化合物 T11189;恩曲他滨 S-氧化物[干冰运输];恩曲他滨S-氧化物(非对映体混合物);恩曲他滨S-氧化物(亚砜手性混合物);恩曲他滨杂质 II(恩曲他滨氧化杂质);化合物 EMTRICITABINE S-OXIDE;(2R,3R,5S)-5-氟-1-[2-羟甲基-3-氧-1,3-氧硫环-5-基]胞嘧啶
- CBNumber:
- CB22545905
- 分子式:
- C8H10FN3O4S
- 分子量:
- 263.2461032
- MOL File:
- 152128-77-3.mol
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恩曲他滨S-氧化物(非对映体混合物)化学性质
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熔点:
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212-213°C (dec.)
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沸点:
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562.8±60.0 °C(Predicted)
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密度:
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2.02±0.1 g/cm3(Predicted)
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储存条件:
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Refrigerator
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溶解度:
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Methanol (Slightly, Heated, Sonicated), Water (Sparingly, Heated)
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酸度系数(pKa):
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13.46±0.10(Predicted)
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形态:
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Solid
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颜色:
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White to Off-White
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恩曲他滨S-氧化物(非对映体混合物)性质、用途与生产工艺
Emtricitabine S-oxide (Emtricitabine sulfoxide) 是 Emtricitabine 的主要降解产物。Emtricitabine 是一种有效的核苷类逆转录酶抑制剂，可用于研究 HIV 感染。
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HIV
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Reverse Transcriptase
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Emtricitabine, an antiretroviral agent is used to evaluate degradation pathways under different stress conditions in order to identify degradation products as prescribed by ICH guidelines. Emtricitabine degrades over 51%, 13% and 53% during acid, base and oxidative degradation respectively followed by formation of three major degradation products (Degradant-I to Degradant-III).
恩曲他滨S-氧化物(非对映体混合物)
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/11/08 | HY-100096 | Emtricitabine S-oxide | | 1 mg | 1035元 |
152128-77-3, 恩曲他滨S-氧化物(非对映体混合物) 相关搜索:
(2R,5S)-5-(5-氟-3,4-二氢-2,4-二氧代-1(2H)-嘧啶基)-1,3-恶噻戊环-2-羧酸(1R,2S,5R)-5-甲基-2-(1-甲基乙基)环己基酯 恩曲他滨杂质22 5-(4-氨基-2-氧代-2H-嘧啶-1-基)-[1,3]1,3-氧硫杂环戊-2-甲酸孟酯 恩曲他滨 恩曲他滨杂质 EmtricitabineTenofovirDisoproxilDimer EmtricitabineImpurity18 (2S)-2-[[[(1,1-Dimethylethyl)diphenylsilyl]oxy]methyl]-1,3-oxathiolan-5-ol5-Acetate [1S-(1α,2α,5β)]-5-甲基-2-(1-甲基乙基)环己醇 恩曲他滨杂质 恩曲他滨 恩曲他滨杂质25 恩曲他滨杂质 ((2S,5R)-5-(4-氨基-5-氟-2-氧亚基嘧啶-1(2H)-基)-1,3-噁噻戊环-2-基)甲基丁酯 恩曲他滨对照品 恩曲他滨5差向异构体 酸性蓝74 恩曲他滨杂质15
- Sulfur & Selenium Compounds
- Pharmaceuticals
- Metabolites & Impurities
- Intermediates & Fine Chemicals
- Heterocycles
- Chiral Reagents
- Carbohydrates & Derivatives
- 抑制剂
- 杂质对照品
- 杂质
- 26325
- C8H10FN3O4S
- 恩曲他滨S-氧化物(亚砜手性混合物)
- 化合物 EMTRICITABINE S-OXIDE
- EMTRICITABINE DEGRADANT-III|||EMTRICITABINE SULFOXIDE
- 化合物 T11189
- 恩曲他滨 S-氧化物[干冰运输]
- 恩曲他滨杂质 II(恩曲他滨氧化杂质)
- 恩曲他滨亚砜
- 恩曲他滨杂质II
- (2R,3R,5S)-5-氟-1-[2-羟甲基-3-氧-1,3-氧硫环-5-基]胞嘧啶
- 恩曲他滨 S-氧化物
- 恩曲他滨S-氧化物(非对映体混合物)
- 152128-77-3
- Emtricitabine S-oxide(Mixture)
- Emtricitabine Sulphoxide Impurity
- (-)-EMtricitabine S-Oxide
(Mixture of DiastereoMers)
- Emtricitabine Sulfoxide Impurity
- Emtricitabine IP Impurity H
- EMTRICITABINE S-OXIDE (EMTRICITABINE SULFOXIDE)
- 4-amino-5-fluoro-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxo-1,3-oxathiolan-5-yl]pyrimidin-2-one
- 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-3-oxo-1,3-oxathiolan-5-yl]pyrimidin-2-one
- Emtricitabine Impurity 2
- EMtricitabine S-Oxide
- Emtricitabine Sulfoxide
- Emtricitabine IP Impurity G
- Emtricitabine Degradant-III
- 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-
- Emtricitabine Sulphoxide
- 4-AMino-5-fluoro-1-[(2R,5S)-2-(hydroxyMethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone
- [2R-(2α,5α)]-4-AMino-5-fluoro-1-[2-(hydroxyMethyl)
-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone S-Oxide
- [2R-(2α,5α)]-4-AMino-5-fluoro-1-
[2-(hydroxyMethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone
- Emtricitabine Impurity
- (-)-EMtricitabine S-Oxide
(Mixture of DiastereoMers)