网站主页 >> CAS数据库列表 >> 1H-吡唑-1-丙腈,Β-环戊基-4-[7-(羟基甲基)-7H-吡咯并[2,3-D]嘧啶-4-基]-,(ΒR)-
1H-吡唑-1-丙腈,Β-环戊基-4-[7-(羟基甲基)-7H-吡咯并[2,3-D]嘧啶-4-基]-,(ΒR)-
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- CAS号:
- 1236033-03-6
- 英文名:
- 1H-Pyrazole-1-propanenitrile, β-cyclopentyl-4-[7-(hydroxyMethyl)-7H-pyrrolo[2,3-d]pyriMidin-4-yl]-,(βR)-
- 英文别名:
- Ruxolitinib lmpurity3;Ruxolitinib Impurity 4;Ruxolitinib N-Methanol;Ruxolitinib Impurity 9;Ruxolitinib Impurity 11;3-(3-bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile;3-(5-bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile;(3R)-3-cyclopentyl-3-[4-[7-(hydroxymethyl)pyrrolo[2,3-d]pyrimidin-4-yl]pyrazol-1-yl]propanenitrile;1H-Pyrazole-1-propanenitrile, β-cyclopentyl-4-[7-(hydroxyMethyl)-7H-pyrrolo[2,3-d]pyriMidin-4-yl]-,(βR)-;(R)-3-cyclopentyl-3-(4-(5-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
- 中文名:
- 1H-吡唑-1-丙腈,Β-环戊基-4-[7-(羟基甲基)-7H-吡咯并[2,3-D]嘧啶-4-基]-,(ΒR)-
- 中文别名:
- 芦可替尼杂质;芦可替尼杂质9;鲁索替尼杂质4;芦可替尼杂质4;芦可替尼杂质06;鲁索利替尼杂质4;芦可替尼杂质11;1H-吡唑-1-丙腈,Β-环戊基-4-[7-(羟基甲基)-7H-吡咯并[2,3-D]嘧啶-4-基]-,(ΒR)-
- CBNumber:
- CB22667045
- 分子式:
- C18H20N6O
- 分子量:
- 336.391
- MOL File:
- 1236033-03-6.mol
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1H-吡唑-1-丙腈,Β-环戊基-4-[7-(羟基甲基)-7H-吡咯并[2,3-D]嘧啶-4-基]-,(ΒR)-化学性质
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沸点:
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621.2±55.0 °C(Predicted)
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密度:
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1.41±0.1 g/cm3(Predicted)
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酸度系数(pKa):
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10.96±0.10(Predicted)
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1H-吡唑-1-丙腈,Β-环戊基-4-[7-(羟基甲基)-7H-吡咯并[2,3-D]嘧啶-4-基]-,(ΒR)-性质、用途与生产工艺
本品是芦可替尼的杂质。芦可替尼是一种选择性Janus酪氨酸激酶(JAK1和JAK2)抑制剂，用于骨髓增生性肿瘤和银屑病的治疗。
1H-吡唑-1-丙腈,Β-环戊基-4-[7-(羟基甲基)-7H-吡咯并[2,3-D]嘧啶-4-基]-,(ΒR)-
上下游产品信息
上游原料
下游产品
1H-吡唑-1-丙腈,Β-环戊基-4-[7-(羟基甲基)-7H-吡咯并[2,3-D]嘧啶-4-基]-,(ΒR)-
生产厂家
1236033-03-6, 1H-吡唑-1-丙腈,Β-环戊基-4-[7-(羟基甲基)-7H-吡咯并[2,3-D]嘧啶-4-基]-,(ΒR)- 相关搜索:
- 通用试剂
- 320-芦可替尼
- 对照品-杂质对照品
- 杂质对照品
- 芦可替尼杂质06
- 鲁索替尼杂质4
- 鲁索利替尼杂质4
- 芦可替尼杂质4
- 芦可替尼杂质
- 芦可替尼杂质9
- 芦可替尼杂质11
- 1H-吡唑-1-丙腈,Β-环戊基-4-[7-(羟基甲基)-7H-吡咯并[2,3-D]嘧啶-4-基]-,(ΒR)-
- 1236033-03-6
- 3-(3-bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
- 3-(5-bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
- (R)-3-cyclopentyl-3-(4-(5-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
- (R)-3-cyclopentyl-3-(4-(7-(hydroxymethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile
- Ruxolitinib lmpurity3
- Ruxolitinib Impurity 9
- Ruxolitinib Impurity 11
- Ruxolitinib Impurity 4
- Ruxolitinib N-Methanol
- (3R)-3-cyclopentyl-3-[4-[7-(hydroxymethyl)pyrrolo[2,3-d]pyrimidin-4-yl]pyrazol-1-yl]propanenitrile
- 1H-Pyrazole-1-propanenitrile, β-cyclopentyl-4-[7-(hydroxyMethyl)-7H-pyrrolo[2,3-d]pyriMidin-4-yl]-,(βR)-