1402837-78-8
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- CAS号:
- 1402837-78-8
- 英文名:
- IDO-IN-7
- 英文别名:
- IDO-IN-7;Navoximod;Navoximod (NLG919);IDO-IN-7(Navoximod);Reaxys ID: 22999399;Navoximod (GDC-0919;Navoximod (Synonyms: GDC-0919;GDC-0917;CUDC427;CUDC 427;GDC0917;GDC 0917;inhibit,Indoleamine 2,3-Dioxygenase (IDO),GDC 0919,Inhibitor,Navoximod,NLG-?919,GDC0919;5H-Imidazo[5,1-a]isoindole-5-ethanol, 6-fluoro-α-(trans-4-hydroxycyclohexyl)-, (αR,5S)-
- 中文名:
- 1402837-78-8
- 中文别名:
- IDO-IN-7抑制剂;化合物NAVOXIMOD;IDO抑制剂(NAVOXIMOD);反式-4-((R)-2-((S)-6-氟-5H-咪唑并[5,1-A]异吲哚-5-基)-1-羟乙基)环己烷-1-醇
- CBNumber:
- CB23048658
- 分子式:
- C18H21FN2O2
- 分子量:
- 316.38
- MOL File:
- 1402837-78-8.mol
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1402837-78-8化学性质
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沸点:
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555.4±35.0 °C(Predicted)
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密度:
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1.42±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO:100.0(Max Conc. mg/mL);316.09(Max Conc. mM)
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形态:
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Solid
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酸度系数(pKa):
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14.66±0.20(Predicted)
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颜色:
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White to light yellow
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1402837-78-8性质、用途与生产工艺
Navoximod (GDC-0919, NLG-919) 是一种有效的 IDO (indoleamine-(2,3)-dioxygenase) 途径的抑制剂,其Ki值为7 nM,EC50值为75 nM。
Target | Value |
IDO
(Cell-free assay)
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7 nM(Ki)
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IDO
(Cell-free assay)
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75 nM(EC50)
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1402837-78-8
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下游产品
更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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2024/08/19 | HY-18770B | 1402837-78-8 Navoximod | 1402837-78-8 | 1mg | 1200元 |
2024/08/19 | HY-18770B | 1402837-78-8 Navoximod | 1402837-78-8 | 5mg | 3600元 |
1402837-78-8, 1402837-78-8 相关搜索:
PURVALANOLA 睾内酯酮 GDC-0077 AGI-6780 4,5-二脱氧-5-(3',5'-二氯[1,1'-联苯]-4-基)-4-[(2-甲氧基乙酰基)氨基]-L-阿拉伯糖酸 6-氨基-8-[(6-碘-1,3-苯并二茂-5-基)硫基]-N-异丙基-9H-嘌呤-9-丙胺 N-[1-(环己基甲基)-4-哌啶基]-2-[六氢-4-异丙基-1H-1,4-二氮杂卓-1-基]-6-甲氧基-7-[3-(1-哌啶基)丙氧基]-4-喹唑啉胺 N4-(5-环丙基-1H-吡唑-3-基)-N2-[[3-异丙基-5-异恶唑基]甲基]-6-(4-甲基-1-哌嗪基)-2,4-嘧啶二胺 N-(3-氯苯基)-N'-[5-[2-(噻吩并[3,2-D]嘧啶-4-基氨基)乙基]-2-噻唑基]脲 β-拉帕醌 4-氨基-N-(3-溴-4-氟苯基)-N'-羟基-1,2,5-恶二唑-3-甲脒 4-氨基-N-(3-氯-4-氟苯基)-N'-羟基-1,2,5-恶二唑-3-甲脒 1-CYCLOHEXYL-2-(5H-IMIDAZO[5,1-A]ISOINDOL-5-YL)ETHANOL 3-(5-氟-1H-吲哚-3-基)-2,5-吡咯烷二酮 1-甲基-D-色氨酸
- api
- 药靶配体
- 小分子抑制剂
- 生物活性分子
- 细胞生物学试剂
- 反式-4-((R)-2-((S)-6-氟-5H-咪唑并[5,1-A]异吲哚-5-基)-1-羟乙基)环己烷-1-醇
- 化合物NAVOXIMOD
- IDO-IN-7抑制剂
- IDO抑制剂(NAVOXIMOD)
- 1402837-78-8
- inhibit,Indoleamine 2,3-Dioxygenase (IDO),GDC 0919,Inhibitor,Navoximod,NLG-?919,GDC0919
- IDO-IN-7(Navoximod)
- Navoximod (NLG919)
- 5H-Imidazo[5,1-a]isoindole-5-ethanol, 6-fluoro-α-(trans-4-hydroxycyclohexyl)-, (αR,5S)-
- Reaxys ID: 22999399
- GDC-0917;CUDC427;CUDC 427;GDC0917;GDC 0917
- Navoximod (Synonyms: GDC-0919
- Navoximod (GDC-0919
- Navoximod
- IDO-IN-7