TL 13-110
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- CAS号:
- 2229037-09-4
- 英文名:
- TL 13-110
- 英文别名:
- TL 13-110;Acetamide, N-[2-[2-[2-[4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-1-piperidinyl]ethoxy]ethoxy]ethyl]-2-[[2,3-dihydro-1,3-dioxo-2-(2-oxo-3-piperidinyl)-1H-isoindol-4-yl]amino]-
- 中文名:
- TL 13-110
- 中文别名:
- CBNumber:
- CB25985160
- 分子式:
- C49H62ClN9O9S
- 分子量:
- 988.59
- MOL File:
- 2229037-09-4.mol
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TL 13-110化学性质
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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TL 13-110性质、用途与生产工艺
TL13-110 是 一种 TL13-112 (HY-123919) 的阴性对照,是一种有效的 ALK 抑制剂,IC50 为 0.34 nM。TL13-110 不会降解细胞中的 ALK。
IC50: 0.34 nM (ALK); 81 μM (Cereblon)
TL13-110 also prompts the degradation of additional kinases including Aurora A, FER, PTK2 and RPS6KA1 with IC
50
values of 9080 nM, 23.1 nM, 21.2 nM, and 480 nM, respectively.
TL 13-110
上下游产品信息
上游原料
下游产品
更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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2024/08/19 | HY-136195 | TL13-110 | | 5 mg | 8791元 |
2229037-09-4, TL 13-110 相关搜索:
- C49H62ClN9O9S
- 2229037-09-4
- Acetamide, N-[2-[2-[2-[4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-1-piperidinyl]ethoxy]ethoxy]ethyl]-2-[[2,3-dihydro-1,3-dioxo-2-(2-oxo-3-piperidinyl)-1H-isoindol-4-yl]amino]-
- TL 13-110