硫酸卡那霉素
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- CAS号:
- 25389-94-0
- 英文名:
- Kanamycin sulfate
- 英文别名:
- KANAMYCIN MONOSULFATE;KANAMYCIN A;KANAMYCIN SULPHATE;KANAMYCIN ACID SULFATE;Kantrex;klebcil;Kanamycin Acid;Kanamycin monosulfate CRS;kano;KAMYCIN
- 中文名:
- 硫酸卡那霉素
- 中文别名:
- 那辛;單硫酸素;单硫酸卡那;卡那霉素A;单硫酸卡那霉;硫酸卡那霉素;单硫酸卡拉霉素;硫酸单卡那霉素;硫酸卡那霉素A;卡那霉素 硫酸酯
- CBNumber:
- CB2722315
- 分子式:
- C18H38N4O15S
- 分子量:
- 582.58
- MOL File:
- 25389-94-0.mol
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硫酸卡那霉素化学性质
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熔点:
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250°C
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比旋光度:
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+112～+123°(D/20℃)(c=1,H2O)(calculated on the dried basis)
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密度:
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1.3619 (rough estimate)
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折射率:
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117.5 ° (C=1, H2O)
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储存条件:
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2-8°C
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溶解度:
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H2O: 10-50 mg/mL As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 5 days.
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形态:
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powder
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颜色:
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white to off-white
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酸碱指示剂变色ph值范围:
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6.5 - 8.5 (1% solution)
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生物来源:
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Streptomyces kanamyceticus
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水溶解性:
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Soluble in water at 10mg/ml
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Merck:
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14,5281
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InChIKey:
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OOYGSFOGFJDDHP-KMCOLRRFSA-N
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硫酸卡那霉素性质、用途与生产工艺
Kanamycin sulfate (Kanamycin monosulfate, Ophtalmokalixan)是一种氨基糖苷类化合物，口服有效，可静脉注射，肌肉注射，广泛应用于感染。
Kanamycin sulfate at the concentration above 0.0025% has a significant inhibition on the growth of B. bifidum and has no influence on the other four probiotics at incubation 12 h or 24 h. The optimum selective concentration of kanamycin sulfate in MRS media is 0.005% for selective enumeration of B.bifidum.
The neurons damage of the DCN caused by kanamycin (500 mg/kg/day) is reversible and autophagy is upregulated in the neurotoxic course of kanamycin on DCN through JNK1-mediated phosphorylation of Bcl-2 pathway in rats. The serum BUN and Cr levels are both increased at the 1st day after the period of kanamycin administration. The neurons expressing LC3 are increased at 1, 7 and 14 days after kanamycin administration in comparison to the control group. Kanamycin treatment results in the increase of autophagy in a time-dependent manner. Kanamycin sulfate (5 mg/kg) and sodium ampicillin (10 mg/kg) administered intramuscularly (i.m.) separately, and then together, to five pony mares, and the ampicillin concentration exceeds 5 mg/mL in inflamed synovial fluid for some 2.5 h after injection, and kanamycin sulfate concentration exceeds 2 mg/mL for 7 h in the pony.
用途
用于治疗食道炎、胃窦炎、细菌性痢疾及消化道感染
用途
生化研究
用途
生物技术的应用，以抑制蛋白质的合成。用于转化细胞用卡那霉素B（neoR，KanR表型）抗性基因作为选择剂。
硫酸卡那霉素
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2025/05/22 | J17924 | 硫酸卡那霉素
Kanamycin sulfateUltrapureThermo Scientific | 25389-94-0 | 25g | 999999元 |
| 2025/05/22 | J17924 | 硫酸卡那霉素
Kanamycin sulfateUltrapureThermo Scientific | 25389-94-0 | 5g | 999999元 |
硫酸卡那霉素
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