司替巴脒
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- CAS号:
- 122-06-5
- 英文名:
- stilbamidine
- 英文别名:
- Ba 2652;Stilbamidin;stilbamidine;4,4'-Stilbenedicarboxamidine;2-(2-phenylethenyl)benzenecarboximidamide;Benzenecarboximidamide, 4,4'-(1,2-ethenediyl)bis-
- 中文名:
- 司替巴脒
- 中文别名:
- 司替巴脒;化合物 T13905
- CBNumber:
- CB2918761
- 分子式:
- C16H16N4
- 分子量:
- 264.33
- MOL File:
- 122-06-5.mol
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司替巴脒化学性质
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沸点:
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397.56°C (rough estimate)
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密度:
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1.1536 (rough estimate)
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折射率:
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1.6000 (estimate)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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司替巴脒性质、用途与生产工艺
Stilbamidine 是 Stilbene 衍生的二脒化合物，主要以其羟乙基磺酸盐形式发挥作用，用于抑制各种真菌感染。
The high-affinity pentamidine transporter (HAPT1) is inhibited by Propamidine but displays only low affinity to Stilbamidine. adenosine-sensitive pentamidine transporter (ASPT1), in contrast, is strongly inhibited by Stilbamidine, and Propamidine. [
3
H]pentamidine uptake is determined in the presence of various concentrations of adenosine (IC
50
=1.2 μM) or melarsen oxide (IC
50
=0.7 μM), as well as in the presence of 250 μM adenosine and increasing concentrations of hypoxanthine, Propamidine (IC
50
=6.1 μM) and Stilbamidine (IC
50
=110 μM). The two diamidine compounds, Stilbamidine and Pentamidine are used to treat in multiple myeloma, a disease in which increase of the globulin content of the serum is of frequent occurrence.
司替巴脒
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2023/03/20 | HY-U00007 | STILBAMIDINE
Stilbamidine | 122-06-5 | 5mg | 6200元 |
122-06-5, 司替巴脒 相关搜索:
- 抑制剂
- 化合物 T13905
- 司替巴脒
- 122-06-5
- Benzenecarboximidamide, 4,4'-(1,2-ethenediyl)bis-
- Stilbamidin
- Ba 2652
- 2-(2-phenylethenyl)benzenecarboximidamide
- 4,4'-Stilbenedicarboxamidine
- stilbamidine