YE-120
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- CAS号:
- 383124-82-1
- 英文名:
- YE-120
- 英文别名:
- YE-120;2-[3-Cyano-5-(3,4-dichloro-phenyl)-4,5-dimethyl-5H-furan-2-ylidene]-malononitrile;2-[3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]propanedinitrile;Propanedinitrile, 2-[3-cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]-
- 中文名:
- YE-120
- 中文别名:
- 化合物 YE 120;化合物 T23542
- CBNumber:
- CB32652554
- 分子式:
- C16H9Cl2N3O
- 分子量:
- 330.17
- MOL File:
- 383124-82-1.mol
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YE-120化学性质
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沸点:
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419.1±45.0 °C(Predicted)
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密度:
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1.42±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble to 100 mM in DMSO
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形态:
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Powder
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颜色:
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White to off-white
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YE-120性质、用途与生产工艺
用途
YE-120 is a GPR35 agonist (EC50 = 32 nM in DMR assays). YE-120 also displays partial agonist activity in a β-arrestin translocation assay (EC50 = 10.2 μM).
GPR35 is a Class A, rhodopsin-like G protei
n-coupled receptor which is predominantly expressed in immune and gastrointestinal tissue, with notable expression in the ileum (rat and human GPR35), the spleen (rat and murine GPR35) and the pancrea
s (human GPR35).
YE-120
上下游产品信息
上游原料
下游产品
383124-82-1, YE-120 相关搜索:
- 抑制剂
- C16H9Cl2N3O
- 化合物 YE 120
- 化合物 T23542
- 383124-82-1
- Propanedinitrile, 2-[3-cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]-
- 2-[3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]propanedinitrile
- 2-[3-Cyano-5-(3,4-dichloro-phenyl)-4,5-dimethyl-5H-furan-2-ylidene]-malononitrile
- YE-120