PubChem ID: 9887472
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- CAS号:
- 194414-69-2
- 英文名:
- PubChem ID: 9887472
- 英文别名:
- PubChem ID: 9887472;Camptothecin-20(S)-O-propionate;Camptothecin20(S)Opropionate,Camptothecin 20(S) O propionate;1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-(1-oxopropoxy)-, (4S)-
- 中文名:
- PubChem ID: 9887472
- 中文别名:
- 化合物 T27113
- CBNumber:
- CB34840469
- 分子式:
- C23H20N2O5
- 分子量:
- 404.42
- MOL File:
- 194414-69-2.mol
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PubChem ID: 9887472化学性质
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熔点:
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250-252 °C (decomp)
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沸点:
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740.3±60.0 °C(Predicted)
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密度:
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1.42±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO: 9.09 mg/mL (22.48 mM)
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形态:
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Solid
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酸度系数(pKa):
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4?+-.0.40(Predicted)
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颜色:
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Off-white to gray
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PubChem ID: 9887472性质、用途与生产工艺
Camptothecin-20(S)-O-propionate (CZ48) 是喜树碱 (CPT) 的类似物，是强效的抗肿瘤化合物。Camptothecin-20(S)-O-propionate (CZ48) 是拓扑异构酶 I (topoisomerase-Ι) 的抑制剂。
Camptothecin-20(S)-O-propionate (CZ48, gavage, 100 to 2000 mg/kg/day) exhibits anti-tumor activity in CLO-breast carcinoma (100 mg/kg) and PC3-prostate carcinoma (1000 mg/kg) models in mice.
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Animal Model:
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A tumor xenograft growing in a nude mouse (size, ∼1 cm
3
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Dosage:
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100-1000 mg/kg/day.
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Administration:
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Oral gavage, for 2, 4 and 6 days, respectively.
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Result:
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Exhibited anti-tumor effect.
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PubChem ID: 9887472
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/08/19 | HY-114668 | Camptothecin-20(S)-O-propionate | | 1 mg | 1200元 |
| 2024/08/19 | HY-114668 | PubChem ID: 9887472
Camptothecin-20(S)-O-propionate | 194414-69-2 | 5mg | 3000元 |
194414-69-2, PubChem ID: 9887472 相关搜索:
- 化合物 T27113
- 194414-69-2
- 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-(1-oxopropoxy)-, (4S)-
- Camptothecin20(S)Opropionate,Camptothecin 20(S) O propionate
- Camptothecin-20(S)-O-propionate
- PubChem ID: 9887472