NEUROPEPTIDE S (HUMAN)
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- CAS号:
- 412938-67-1
- 英文名:
- NEUROPEPTIDE S (HUMAN)
- 英文别名:
- NPS (HUMAN);SFRNGVGTGMKKTSFQRAKS;NEUROPEPTIDE S (HUMAN);Neuropeptide S, NPS, human;Neuropeptide S (huMan)
NPS (huMan);SER-PHE-ARG-ASN-GLY-VAL-GLY-THR-GLY-MET-LYS-LYS-THR-SER-PHE-GLN-ARG-ALA-LYS-SER;H-SER-PHE-ARG-ASN-GLY-VAL-GLY-THR-GLY-MET-LYS-LYS-THR-SER-PHE-GLN-ARG-ALA-LYS-SER-OH;REF DUPL: H-Ser-Phe-Arg-Asn-Gly-Val-Gly-Ser-Gly-Ala-Lys-Lys-Thr-Ser-Phe-Arg-Arg-Ala-Lys-Gln-OH;L-Serine, L-seryl-L-phenylalanyl-L-arginyl-L-asparaginylglycyl-L-valylglycyl-L-threonylglycyl-L-methionyl-L-lysyl-L-lysyl-L-threonyl-L-seryl-L-phenylalanyl-L-glutaminyl-L-arginyl-L-alanyl-L-lysyl-
- 中文名:
- NEUROPEPTIDE S (HUMAN)
- 中文别名:
- 神经肽S (人类);内源性神经肽S受体激动剂,人源;神经肽S (人类)、 NEURO PEPTIDE S (HUMAN);L-丝氨酰-L-苯丙氨酰-L-精氨酰-L-天冬氨酰胺酰甘氨酰-L-缬氨酰甘氨酰-L-苏氨酰甘氨酰-L-蛋氨酰-L-赖氨酰-L-赖氨酰-L-苏氨酰-L-丝氨酰-L-苯丙氨酰-L-谷氨酰胺酰-L-精氨酰-L-丙氨酰-L-赖氨酰-L-丝氨酸
- CBNumber:
- CB4106928
- 分子式:
- C93H155N31O28S
- 分子量:
- 2187.48
- MOL File:
- 412938-67-1.mol
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NEUROPEPTIDE S (HUMAN)化学性质
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密度:
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1.49±0.1 g/cm3(Predicted)
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形态:
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Solid
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颜色:
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White to off-white
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NEUROPEPTIDE S (HUMAN)性质、用途与生产工艺
Neuropeptide S human 是有效的内源性 neuropeptide S receptor 激动剂 (EC50=9.4 nM)。Neuropeptide S human (TFA) 可提高小鼠的运动活性和清醒性。Neuropeptide S human 有潜力用于阿尔茨海默症 (AD) 的研究。
EC50: 9.4 nM (neuropeptide S receptor)
Neuropeptide S human (4 pM to 1.7 nM; 48 hours) retains full agonist activity with an EC
50
of 6.7 ± 2.4 nM, the binding of [
125I
] Y10-hNPS to CHO cells stably expressing hNPSR is saturable with high affinity (K
d
= 0.33 ± 0.12 nM).
Neuropeptide S human (1 pM-3 μM; 48 hours) are used to compete with 0.15 nM [
125I
I] Y10-NPS, [
125I
I] Y10-NPS is displaceable by increasing concentrations of human NPS (IC
50
= 0.42 ± 0.12 nM).
Neuropeptide S human (0.1 nM-1 nM; i.c.v.) causes a significant increase in locomotor activity, the total distance traveled, percentage of time moving, number of rearing events, and center entries are also significantly increased in mice.
Animal Model:
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Male C57Bl/6 mice
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Dosage:
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0.1 nM, 1 nM
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Administration:
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Intracerebroventricular (i.c.v.) injection
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Result:
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Increased locomotor activity and promoted wakefulness.
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NEUROPEPTIDE S (HUMAN)
上下游产品信息
上游原料
下游产品
更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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2024/08/19 | HY-P1389 | Neuropeptide S (human) | | 1 mg | 2500元 |
2024/08/19 | HY-P1389 | Neuropeptide S (human) | | 5 mg | 6200元 |
NEUROPEPTIDE S (HUMAN)
生产厂家
412938-67-1, NEUROPEPTIDE S (HUMAN) 相关搜索:
- peptide
- Various peptides
- 目录肽
- 标准品
- 多肽
- 神经肽S (人类)、 NEURO PEPTIDE S (HUMAN)
- 内源性神经肽S受体激动剂,人源
- L-丝氨酰-L-苯丙氨酰-L-精氨酰-L-天冬氨酰胺酰甘氨酰-L-缬氨酰甘氨酰-L-苏氨酰甘氨酰-L-蛋氨酰-L-赖氨酰-L-赖氨酰-L-苏氨酰-L-丝氨酰-L-苯丙氨酰-L-谷氨酰胺酰-L-精氨酰-L-丙氨酰-L-赖氨酰-L-丝氨酸
- 神经肽S (人类)
- 412938-67-1
- L-Serine, L-seryl-L-phenylalanyl-L-arginyl-L-asparaginylglycyl-L-valylglycyl-L-threonylglycyl-L-methionyl-L-lysyl-L-lysyl-L-threonyl-L-seryl-L-phenylalanyl-L-glutaminyl-L-arginyl-L-alanyl-L-lysyl-
- Neuropeptide S (huMan)
NPS (huMan)
- Neuropeptide S, NPS, human
- REF DUPL: H-Ser-Phe-Arg-Asn-Gly-Val-Gly-Ser-Gly-Ala-Lys-Lys-Thr-Ser-Phe-Arg-Arg-Ala-Lys-Gln-OH
- H-SER-PHE-ARG-ASN-GLY-VAL-GLY-THR-GLY-MET-LYS-LYS-THR-SER-PHE-GLN-ARG-ALA-LYS-SER-OH
- NEUROPEPTIDE S (HUMAN)
- NPS (HUMAN)
- SER-PHE-ARG-ASN-GLY-VAL-GLY-THR-GLY-MET-LYS-LYS-THR-SER-PHE-GLN-ARG-ALA-LYS-SER
- SFRNGVGTGMKKTSFQRAKS