MJ 33
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- CAS号:
- 199106-13-3
- 英文名:
- MJ 33
- 英文别名:
- MJ33-OH;Phosphoric acid, mono[1-[(hexadecyloxy)methyl]-2-(2,2,2-trifluoroethoxy)ethyl] mono(hydroxymethyl) ester
- 中文名:
- MJ 33
- 中文别名:
- MJ33 锂盐
- CBNumber:
- CB4503837
- 分子式:
- C22H44F3O7P
- 分子量:
- 508.55
- MOL File:
- 199106-13-3.mol
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MJ 33化学性质
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储存条件:
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2-8°C
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溶解度:
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H2O: ≥5mg/mL (warmed at 60 °C)
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形态:
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solid
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颜色:
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white to beige
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MJ 33性质、用途与生产工艺
MJ33-OH 是 MJ33 的代谢产物。MJ33 是一种活性位点定向的、特异的、竞争性的和可逆性的磷脂酶 A2 (PLA2) 抑制剂。MJ33 阻断 Prdx6 的非钙依赖性磷脂酶A2 (iPLA2) 活性。
MJ33 (0.5 μM/kg; by tail vein, at 24 h before MCAO) significantly blocks the increase IL-1β, IL-17 and IL-23 in rats stimulated by Prdx6 siRNA treatment.
Compared with the Prdx6 siRNA group, combined exposure to Prdx6 siRNA and MJ33 significantly downregulates the mRNA and protein expression of NF-κB, iNOS and COX-2.
MJ 33
上下游产品信息
上游原料
下游产品
199106-13-3, MJ 33 相关搜索:
- C22H44F3O7P
- C22H43F3O6PLi
- MJ33 锂盐
- 199106-13-3
- MJ33-OH
- Phosphoric acid, mono[1-[(hexadecyloxy)methyl]-2-(2,2,2-trifluoroethoxy)ethyl] mono(hydroxymethyl) ester