Α-突刺蛋白61-75
|
|
|
- CAS号:
- 440645-08-9
- 英文名:
- L-Threonine, L-α-glutamyl-L-glutaminyl-L-valyl-L-threonyl-L-asparaginyl-L-valylglycylglycyl-L-alanyl-L-valyl-L-valyl-L-threonylglycyl-L-valyl-
- 英文别名:
- α-Synuclein (61-75);L-Threonine, L-α-glutamyl-L-glutaminyl-L-valyl-L-threonyl-L-asparaginyl-L-valylglycylglycyl-L-alanyl-L-valyl-L-valyl-L-threonylglycyl-L-valyl-
- 中文名:
- Α-突刺蛋白61-75
- 中文别名:
- Α-突刺蛋白61-75
- CBNumber:
- CB48382669
- 分子式:
- C60H103N17O23
- 分子量:
- 1430.58
- MOL File:
- 440645-08-9.mol
|
|
|
Α-突刺蛋白61-75化学性质
-
沸点:
-
1886.8±65.0 °C(Predicted)
-
|
-
密度:
-
1.304±0.06 g/cm3(Predicted)
-
|
-
酸度系数(pKa):
-
3.23±0.10(Predicted)
-
|
Α-突刺蛋白61-75性质、用途与生产工艺
α-Synuclein (61-75) 是 α-Synuclein 的 61-75 片段。α-Synuclein 是一种丰富的神经元蛋白，在突触前神经末梢高度丰富。α-Synuclein 是一种帕金森氏病 (PD) 的生物标志物。
Lewy bodies containing α-Synuclein are a neuropathological hallmark of PD, and missense mutations in α-Synuclein (A30P, E46K, H50Q, G51D, A53E, A53T), as well as α-Synuclein gene duplications and triplications, appear to cause PD. Moreover, polymorphisms in regulatory elements of the α-Synuclein gene predispose individuals to PD and are linked to an early onset of the disease. The non-Aβ-amyloid component (NAC) region of α-synuclein is relatively hydrophobic and aggregation-prone in human α-Synuclein but not in mouse α-Synuclein nor in the corresponding homologous region of human β-synuclein. Yet, β-synuclein is more homologous to α-synuclein in the N-terminal sequences (74%) than γ-synuclein (67%).
Α-突刺蛋白61-75
上下游产品信息
上游原料
下游产品
440645-08-9, Α-突刺蛋白61-75 相关搜索:
- 目录肽
- C60H103N17O23
- Α-突刺蛋白61-75
- 440645-08-9
- α-Synuclein (61-75)
- L-Threonine, L-α-glutamyl-L-glutaminyl-L-valyl-L-threonyl-L-asparaginyl-L-valylglycylglycyl-L-alanyl-L-valyl-L-valyl-L-threonylglycyl-L-valyl-