4,7-二羟基-2-甲氧基-9,10-二氢菲
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- CAS号:
- 87530-30-1
- 英文名:
- 7-Methoxy-9,10-dihydrophenanthrene-2,5-diol
- 英文别名:
- Lusianthridin;Lusianthridin,Myc,Inhibitor,c-Myc,inhibit;9,10-Dihydro-2-methoxyphenanthrene-4,7-diol;7-Methoxy-9,10-dihydrophenanthrene-2,5-diol;2,5-Phenanthrenediol, 9,10-dihydro-7-methoxy-;4,7-dihydroxy-2-methoxy-9,10-dihydrophenanthrene
- 中文名:
- 4,7-二羟基-2-甲氧基-9,10-二氢菲
- 中文别名:
- 4,7-二羟基-2-甲氧基-9,10-二氢菲
- CBNumber:
- CB52252789
- 分子式:
- C15H14O3
- 分子量:
- 242.27
- MOL File:
- 87530-30-1.mol
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4,7-二羟基-2-甲氧基-9,10-二氢菲化学性质
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沸点:
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507.3±50.0 °C(Predicted)
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密度:
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1.296±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
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形态:
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Powder
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酸度系数(pKa):
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9.23±0.20(Predicted)
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颜色:
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White to off-white
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4,7-二羟基-2-甲氧基-9,10-二氢菲性质、用途与生产工艺
Lusianthridin 是来自 Dendrobium venustum 的天然化合物，具有抗迁移作用。Lusianthridin 通过抑制Src-STAT3 信号，促进c-Myc 的降解。
Lusianthridin (0-100 μM) inhibits cell viability at concentrations greater than 50 μM in both H460 and H292 cells.
Lusianthridin significantly reduces the CSC populations in both H460 and H292 cells of the CSC spheres, with a significant decrease in the size of the H460 CSC spheres by approximately 10%, 63%, and 77% at day 3 at concentration 5, 10, and 20 μM Lusianthridin, respectively.
Cell Viability Assay
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Cell Line:
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The human non-small cell lung cancer cell lines, NCI-H460, and NCI-H292 cells
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0-100 μM.
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Concentration:
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0-100 μM.
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Incubation Time:
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24 h.
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Result:
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Caused a significant reduction in terms of cell viability at concentrations greater than 50 μM in both H460 and H292 cells.
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4,7-二羟基-2-甲氧基-9,10-二氢菲
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/11/08 | HY-121418 | Lusianthridin | | 1 mg | 3200元 |
| 2023/03/20 | HY-121418 | 4,7-二羟基-2-甲氧基-9,10-二氢菲
Lusianthridin | 87530-30-1 | 5mg | 11500元 |
4,7-二羟基-2-甲氧基-9,10-二氢菲
生产厂家
87530-30-1, 4,7-二羟基-2-甲氧基-9,10-二氢菲 相关搜索:
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- 标准品，对照品
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- 对照品
- 4,7-二羟基-2-甲氧基-9,10-二氢菲
- 87530-30-1
- Lusianthridin,Myc,Inhibitor,c-Myc,inhibit
- 2,5-Phenanthrenediol, 9,10-dihydro-7-methoxy-
- 4,7-dihydroxy-2-methoxy-9,10-dihydrophenanthrene
- Lusianthridin
- 9,10-Dihydro-2-methoxyphenanthrene-4,7-diol
- 7-Methoxy-9,10-dihydrophenanthrene-2,5-diol