CCG1423

CCG1423性质、用途与生产工艺

生物活性

CCG-1423是一种特定的 RhoA 通路抑制剂，能够抑制SRF介导的转录。

体外研究

CCG-1423 selectively inhibits SRF-mediated transcription activated by Rho pathway signaling, and specifically inhibits LPA-stimulated DNA synthesis. CCG-1423 also selectively inhibits the proliferation of RhoC-overexpressing melanoma cells (A375M2 and SK-Mel-147), and strongly suppresses the Rho-dependent invasion by PC-3 cells. CCG-1423 in combination with LY294002 enhances differentiation of mouse embryonic stem cells into intermediate mesoderm through BMP7-positive cells. In H9c2 cells, CCG-1423 inhibits MRTF nuclear localization, and completely blocks STARS proximal reporter activity. CCG-1423, as a Rho/MRTF/SRF pathway inhibitor, also represses both matrix-stiffness and TGF-beta-induced fibrogenesis in human colonic myofibroblasts.

CCG1423 上下游产品信息

上游原料

下游产品

CCG1423 试剂级价格

更新日期	产品编号	产品名称	CAS编号	包装	价格
2024/11/08	HY-13991	CCG-1423		5 mg	406元
2024/11/08	HY-13991	CCG1423 CCG-1423	285986-88-1	10mg	650元

CCG1423 生产厂家

 

285986-88-1, CCG1423 相关搜索:

• Inhibitors
• 合成有机化合物配体
• 细胞生物学试剂
• 小分子抑制剂，天然产物
• 小分子抑制剂
• 抑制剂
• C18H13ClF6N2O3
• CCG 1423,RHO PATHWAY-MEDIATED SIGNALING抑制剂
• CCG 1423,RHO / SRF通路抑制剂
• N-((1-((4-氯苯基)氨基)-1-氧代丙烷-2-基)氧基)-3,5-双(三氟甲基)苯甲酰胺
• RHOA/C介导基因转录抑制剂(CCG-1423)
• N-[2-[(4-氯苯基)氨基]-1-甲基-2-氧代乙氧基]-3,5-二(三氟甲基)苯甲酰胺
• N-({1-[(4-氯苯基)氨基]-1-氧代-2-丙基}氧基)-3,5-二(三氟甲基)苯甲酰胺
• 285986-88-1
• CCG 1423, Rho pathway-mediated signaling inhibitor
• CC -1423
• Rho/SRF Pathway Inhibitor, CCG-1423 - CAS 285986-88-1 - Calbiochem
• CCG 1423;CCG-1423
• CCG1423, >98%
• CS-1769
• CCg
• Benzamide, N-[2-[(4-chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)-
• CCG-1423 USP/EP/BP
• Rho/SRF Pathway Inhibitor, CCG-1423
• N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide
• N-[2-[(4-Chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)-benzamide
• N-({1-[(4-Chlorophenyl)Amino]-1-Oxo-2-Propanyl}Oxy)-3,5-Bis(Trifluoromethyl)Benzamide CCG-1423
• N-(1-(4-chlorophenylaMino)-1-oxopropan-2-yloxy)-3,5-bis(trifluoroMethyl)benzaMide
• N-(2-(4-Chloroanilino)-1-Methyl-2-oxoethoxy)-3,5-bis(trifluoroMethyl)benzaMide
• CCG-1423