苦参醇K
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- CAS号:
- 101236-49-1
- 英文名:
- Kushenol K
- 英文别名:
- Kushenol K;product/154906;(2R,3S)-2-(2,4-Dihydroxyphenyl)-2,3-dihydro-3,7-dihydroxy-8-[(2R)-5-hydroxy-5-methyl-2-(1-methylethenyl)hexyl]-5-methoxy-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-3,7-dihydroxy-8-[(2R)-5-hydroxy-5-methyl-2-(1-methylethenyl)hexyl]-5-methoxy-, (2R,3S)-
- 中文名:
- 苦参醇K
- 中文别名:
- 苦参醇K;苦参醇K标准品;苦参醇K对照品
- CBNumber:
- CB53034759
- 分子式:
- C26H32O8
- 分子量:
- 472.53
- MOL File:
- 101236-49-1.mol
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苦参醇K化学性质
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溶解度:
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Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
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形态:
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Powder
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苦参醇K性质、用途与生产工艺
Kushenol K,一种从 Sophora flavescens 中提取的黄酮类抗氧化剂。Kushenol K 是 CYP3A4 的抑制剂,Ki 值为 1.35 μM。Kushenol K 对 HSV-2 具有较弱的抗病毒活性 (EC50 为 147 μM)。Kushenol K 还抑制 SGLT1 和 SGLT2 的活性。
HSV-2
147 μM (EC
50
)
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CYP3A4
1.35 μM (Ki)
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SGLT
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When Midazolam is used as the substrate of CYP3A4, Kushenol K exhibits the strong inhibition with an IC
50
values of 1.62 µM.
At a concentration of 50 μM, the inhibition rate of Kushenol K on SGLT1 is 29.7%, and the inhibition rate on SGLT2 is 43.7%.
苦参醇K
上下游产品信息
上游原料
下游产品
101236-49-1, 苦参醇K 相关搜索:
- 标准品
- 标准品,对照品
- 标准品 -中药标准品
- 对照品
- 中药对照品
- 植物提取物
- 苦参醇K标准品
- 苦参醇K对照品
- 苦参醇K
- 101236-49-1
- 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-3,7-dihydroxy-8-[(2R)-5-hydroxy-5-methyl-2-(1-methylethenyl)hexyl]-5-methoxy-, (2R,3S)-
- product/154906
- (2R,3S)-2-(2,4-Dihydroxyphenyl)-2,3-dihydro-3,7-dihydroxy-8-[(2R)-5-hydroxy-5-methyl-2-(1-methylethenyl)hexyl]-5-methoxy-4H-1-benzopyran-4-one
- Kushenol K