网站主页 >> CAS数据库列表 >> 2-(3-(6-(2-(2,4-二氯苯基)乙基氨基)-2-甲氧基嘧啶-4-基)苯基)-2-甲基丙酸
2-(3-(6-(2-(2,4-二氯苯基)乙基氨基)-2-甲氧基嘧啶-4-基)苯基)-2-甲基丙酸
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- CAS号:
- 885066-67-1
- 英文名:
- PGD2-inhibitor
- 英文别名:
- MDK66671;PGD2-IN-1;PGD2-inhibitor;PGD2 inhibitor 1;PGD2-IN-1?, >98%;PGD2-inhibitor, >98%;prostaglandin D2(PGD2) inhibitor;Benzeneacetic acid, 3-[6-[[2-(2,4-dichlorophenyl)ethyl]amino]-2-methoxy-4-pyrimidinyl]-α,α-dimethyl-;Benzeneacetic acid, 3-[6-[[2-(2,4-dichlorophenyl)ethyl]amino]-2-methoxy-4-pyrimidinyl]-α,α-dimethyl-
- 中文名:
- 2-(3-(6-(2-(2,4-二氯苯基)乙基氨基)-2-甲氧基嘧啶-4-基)苯基)-2-甲基丙酸
- 中文别名:
- 化合物PGD2-INHIBITOR;2-(3-(6-(2-(2,4-二氯苯基)乙基氨基)-2-甲氧基嘧啶-4-基)苯基)-2-甲基丙酸
- CBNumber:
- CB53146427
- 分子式:
- C23H23Cl2N3O3
- 分子量:
- 460.35
- MOL File:
- 885066-67-1.mol
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2-(3-(6-(2-(2,4-二氯苯基)乙基氨基)-2-甲氧基嘧啶-4-基)苯基)-2-甲基丙酸化学性质
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沸点:
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682.1±65.0 °C(Predicted)
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密度:
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1.326±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO : ≥ 25 mg/mL (54.31 mM)
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形态:
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Solid
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酸度系数(pKa):
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4.09±0.10(Predicted)
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颜色:
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White to off-white
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2-(3-(6-(2-(2,4-二氯苯基)乙基氨基)-2-甲氧基嘧啶-4-基)苯基)-2-甲基丙酸性质、用途与生产工艺
PGD2-IN-1 是DP受体拮抗剂, 来自专利专利WO 2006044732 A2，化合物实例15 (d)， IC50值为0.3 nM。
Prostaglandin D2 (PGD2) is a major inflammatory mediator implicated in asthma and allergic rhinitis. It is largely produced as the major cyclooxygenase metabolite upon allergen-provoked degranulation from mast cells. Blockage of PGD2 using DP antagonists has been shown to be effective at alleviating the symptoms of allergic rhinitis in multiple species and more specifically has been shown to inhibit the antigen-induced nasal congestion.
2-(3-(6-(2-(2,4-二氯苯基)乙基氨基)-2-甲氧基嘧啶-4-基)苯基)-2-甲基丙酸
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/04/30 | HY-101430 | 2-(3-(6-(2-(2,4-二氯苯基)乙基氨基)-2-甲氧基嘧啶-4-基)苯基)-2-甲基丙酸
PGD2-IN-1 | 885066-67-1 | 5mg | 1800元 |
| 2024/04/30 | HY-101430 | 2-(3-(6-(2-(2,4-二氯苯基)乙基氨基)-2-甲氧基嘧啶-4-基)苯基)-2-甲基丙酸
PGD2-IN-1 | 885066-67-1 | 10mM * 1mLin DMSO | 1823元 |
2-(3-(6-(2-(2,4-二氯苯基)乙基氨基)-2-甲氧基嘧啶-4-基)苯基)-2-甲基丙酸
生产厂家
885066-67-1, 2-(3-(6-(2-(2,4-二氯苯基)乙基氨基)-2-甲氧基嘧啶-4-基)苯基)-2-甲基丙酸 相关搜索:
- 2-(3-(6-(2-(2,4-二氯苯基)乙基氨基)-2-甲氧基嘧啶-4-基)苯基)-2-甲基丙酸
- 化合物PGD2-INHIBITOR
- 885066-67-1
- Benzeneacetic acid, 3-[6-[[2-(2,4-dichlorophenyl)ethyl]amino]-2-methoxy-4-pyrimidinyl]-α,α-dimethyl-
- Benzeneacetic acid, 3-[6-[[2-(2,4-dichlorophenyl)ethyl]amino]-2-methoxy-4-pyrimidinyl]-α,α-dimethyl-
- PGD2 inhibitor 1
- prostaglandin D2(PGD2) inhibitor
- PGD2-inhibitor, >98%
- PGD2-IN-1?, >98%
- MDK66671
- PGD2-IN-1
- PGD2-inhibitor