1636881-61-2
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- CAS号:
- 1636881-61-2
- 英文名:
- Mavoglurant (racemate)
- 英文别名:
- AFQ-056 racemate;Mavoglurant (racemate);1H-Indole-1-carboxylic acid, octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-, methyl ester, (3aR,4S,7aR)-rel-
- 中文名:
- 1636881-61-2
- 中文别名:
- 化合物 T11951
- CBNumber:
- CB53160072
- 分子式:
- C19H23NO3
- 分子量:
- 313.39
- MOL File:
- 1636881-61-2.mol
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1636881-61-2化学性质
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沸点:
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476.3±45.0 °C(Predicted)
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密度:
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1.21±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO : 50 mg/mL (159.55 mM)
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形态:
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Solid
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酸度系数(pKa):
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12.75±0.20(Predicted)
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颜色:
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White to off-white
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1636881-61-2性质、用途与生产工艺
Mavoglurant racemate (AFQ-056 racemate) 是 Mavoglurant 的外消旋体。Mavoglurant 是一种新颖的,非竞争性的 mGlu5 受体拮抗剂。
For antagonistic activity, (−)-mavoglurant, the (−)-enantiomer shows IC
50
of 0.11 μM and 0.03 μM (Ca
2+
and PI-turnover) whereas the (+)-enantiomer ((+)-10) shows only 37% and 18% inhibition at 10 μM.
1636881-61-2
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下游产品
更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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2024/08/19 | HY-15257A | 1636881-61-2 Mavoglurant racemate | 1636881-61-2 | 2mg | 3500元 |
2024/08/19 | HY-15257A | 1636881-61-2 Mavoglurant racemate | 1636881-61-2 | 5mg | 7000元 |
1636881-61-2, 1636881-61-2 相关搜索:
- 化合物 T11951
- 1636881-61-2
- 1H-Indole-1-carboxylic acid, octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-, methyl ester, (3aR,4S,7aR)-rel-
- AFQ-056 racemate
- Mavoglurant (racemate)