GAK inhibitor 49
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- CAS号:
- 319492-82-5
- 英文名:
- GAK inhibitor 49
- 英文别名:
- AK inhibitor 49;GAK inhibitor 49;6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine;4-Quinolinamine, 6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)-;NAK,selective,GAK inhibitor-49,GAK inhibitor49,GAK inhibitor 49,Inhibitor,inhibit,ATP-competitive,family
- 中文名:
- GAK inhibitor 49
- 中文别名:
- GAK抑制剂49;化合物GAK INHIBITOR 49;6,7-二甲氧基-N-(3,4,5-三甲氧基苯基)喹啉-4-胺
- CBNumber:
- CB54667925
- 分子式:
- C20H22N2O5
- 分子量:
- 370.4
- MOL File:
- 319492-82-5.mol
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GAK inhibitor 49化学性质
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沸点:
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494.8±45.0 °C(Predicted)
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密度:
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1.223±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO: 50 mg/mL (134.99 mM; ultrasonic and warming and heat to 80°C)
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酸度系数(pKa):
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7?+-.0.50(Predicted)
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形态:
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Solid
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颜色:
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White to off-white
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GAK inhibitor 49性质、用途与生产工艺
GAK inhibitor 49 是一种 ATP 竞争性的、高选择性细胞周期蛋白G相关激酶 (GAK) 抑制剂，Ki 为 0.54 nM，细胞 IC50 为 56 nM。GAK inhibitor 49 也显示与 RIPK2 结合。
GAK inhibitor 49 (compound 49) shows a weak inhibitory effect on AAK1, BMP2K and STK16, with IC
50
s of 28, 63 and >100 μM, respectively.
GAK inhibitor 49
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/11/08 | HY-124793 | GAK inhibitor 49 | | 1 mg | 1000元 |
| 2024/11/08 | HY-124793 | GAK inhibitor 49
GAK inhibitor 49 | 319492-82-5 | 5mg | 2500元 |
319492-82-5, GAK inhibitor 49 相关搜索:
- 抑制剂
- 药靶配体
- GAK抑制剂49
- 6,7-二甲氧基-N-(3,4,5-三甲氧基苯基)喹啉-4-胺
- 化合物GAK INHIBITOR 49
- 319492-82-5
- AK inhibitor 49
- NAK,selective,GAK inhibitor-49,GAK inhibitor49,GAK inhibitor 49,Inhibitor,inhibit,ATP-competitive,family
- 6,7-Dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
- 4-Quinolinamine, 6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)-
- GAK inhibitor 49