SP-ADENOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE TRIETHYLAMINE

生物活性靶点体外研究体内研究

CAS号:: 73208-40-9

英文名:: SP-ADENOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE TRIETHYLAMINE

英文别名:: SP-CAMPS TEA;(R)-Adenosine;CAMPS TEA, SP-ISOMER;cAMPS-Rp, triethylam;SP-CAMPS TRIETHYLAMINE;RP-CAMPS TRIETHYLAMINE;SP-CAMPS TRIETHYL AMMONIUM SALT;CAMPS-SP, TRIETHYLAMMONIUM SALT;Cyclic3',5'-(hydrogenphosphorothioate)triethylammonium;SP-ADENOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE TRIETHYLAMINE

中文名:

中文别名:

CBNumber:: CB5699120

分子式:: C16H27N6O5PS

分子量:: 446.46

MOL File:: 73208-40-9.mol

化学性质安全信息用途供应商 27

SP-ADENOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE TRIETHYLAMINE化学性质

储存条件:: −20°C

溶解度:: H₂O: soluble

形态:: solid

颜色:: white

安全信息

安全说明:	22-24/25

WGK Germany:	3

SP-ADENOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE TRIETHYLAMINE性质、用途与生产工艺

生物活性

Rp-cAMPS，一种 cAMP 的类似物，是一种 cAMP 诱导的 PKA I 和 PKA II 活化 (Ki 分别为 12.5 µM 和 4.5 µM) 的有效的，竞争性拮抗剂。Rp-cAMPS 耐磷酸二酯酶水解。

靶点

Ki: 6.05 µM (PKA I) and 9.75 µM (PKA II)

A membrane-permeable competitive cAMP antagonist (Rp-cAMPS) that blocks PKA activation by binding to the regulatory subunits without dissociating the kinase holoenzyme also inhibits synaptic plasticity but has no effect on normal synaptic transmission.

体内研究

Rp-cAMPS (10 μM, 15 min) decreases the monosynaptic EPSCs evoked at the PB-CeLC and BLA-CeLC synapses in slices from arthritic rats but not in control neurons from normal animals. The inhibitory effect of Rp-cAMPS is significant compared to predrug (ACSF) control values obtained in the same neurons.

SP-ADENOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE TRIETHYLAMINE 上下游产品信息

上游原料

下游产品

SP-ADENOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE TRIETHYLAMINE 生产厂家

全球有 27家供应商 SP-ADENOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE TRIETHYLAMINE国内生产厂家

供应商	联系电话	电子邮件	国家	产品数	优势度
武汉易泰科技有限公司上海分公司	821-50328103-801 18930552037	3bsc@sina.com	中国	15848	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	美国	8449	60
上海一飞生物科技有限公司	021-65675885 18964387627	info@efebio.com	中国	9708	58
北京迈瑞达科技有限公司	010-82387566 18001021521	sales@mreda.com.cn	中国	21450	58
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	sales@newcanbio.com	中国	9980	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	美国	19743	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	美国	19892	58
BOC Sciences	16314854226	inquiry@bocsci.com	美国	9713	58
MedBio脉铂医药	021-69568360 18916172912	order@med-bio.cn	中国	8141	58
天津普西唐生物医药科技有限公司	010-60605840	psaitong@jm-bio.com	中国	29778	58
上海优宁维生物科技股份有限公司	18768175414	gaojun@univ-bio.com	中国	24998	58
ApexBio技术		sales@apexbt.com	美国	6254	58
Carbosynth		sales@carbosynth.com	英国	6018	58

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Cyclic Nucleotide related
Cyclic Nucleotides and Analogs
Cyclic Nucleotide Metabolism
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Cell Biology
Cell Signaling and Neuroscience
BioChemical
C10H12N5O5PSC6H15N
73208-40-9
cAMPS-Rp, triethylam
ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER TRIETHYL AMMONIUM SALT
CAMPS-SP, TRIETHYLAMMONIUM SALT
CAMPS TEA, SP-ISOMER
Adenosine-3'',5''-cyclic monophosphothioate sodium salt Rp isomer
RP-CAMPS TRIETHYLAMINE
RP-ADENOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE TRIETHYLAMINE
(S)-ADENOSINE, CYCLIC 3',5'-(HYDROGENPHOSPHOROTHIOATE) TRIETHYLAMMONIUM SALT
SP-CAMPS TRIETHYL AMMONIUM SALT
SP-CAMPS TRIETHYLAMINE
SP-CAMPS TEA
SP-CYCLIC 3',5'-HYDROGEN PHOSPHOROTHIOATE ADENOSINE TRIETHYLAMINE
SP-ADENOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE TRIETHYLAMINE
adenosine-3’,5’-cyclicmonophosphorothioate,rp-isomer(rp-camps),sodiumsalt
Rp-Adenosine 3′,5′-cyclic Monophosphorothioate, Sodium Salt
(R)-Adenosine,cyclic3',5'-(hydrogenphosphorothioate)triethylammonium
Cyclic3',5'-(hydrogenphosphorothioate)triethylammonium
(R)-Adenosine
ADENOSINE 3',5'-CYCLIC PHOSPHOROTHIOATE-SP, TRIETHYLAMMONIUM SALT
ADENOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE, SP-ISOMER TRIETHYLAMMONIUM SALT