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Uridine 5'-(trihydrogen diphosphate), 4-oxime (9CI)
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- CAS号:
- 39023-73-9
- 英文名:
- Uridine 5'-(trihydrogen diphosphate), 4-oxime (9CI)
- 英文别名:
- NHC-diphosphate;Uridine 5'-(trihydrogen diphosphate), 4-oxime (9CI)
- 中文名:
- 中文别名:
- CBNumber:
- CB58132214
- 分子式:
- C9H15N3O12P2
- 分子量:
- 419.18
- MOL File:
- 39023-73-9.mol
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Uridine 5'-(trihydrogen diphosphate), 4-oxime (9CI)化学性质
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密度:
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2.37±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C, protect from light, stored under nitrogen
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酸度系数(pKa):
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1.39±0.10(Predicted)
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形态:
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Solid
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颜色:
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White to off-white
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水溶解性:
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Water : 160 mg/mL (381.70 mM)
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Uridine 5'-(trihydrogen diphosphate), 4-oxime (9CI)性质、用途与生产工艺
NHC-diphosphate 是 NHC (HY-125033) 的活性胞内磷酸化代谢物 (intracellular metabolite )，以二磷酸盐的形式存在。NHC 是一种嘧啶核糖核苷，是一种有效的抗病毒剂 (anti-virus agent)。NHC 有效抑制委内瑞拉马脑炎病毒 (VEEV)、基孔肯亚病毒 (CHIKV) 和丙型肝炎病毒 (HCV) 的复制。
Huh-7 cells are incubated with (10-50 μM; 4 h) NHC or a McGuigan phosphoramidate prodrug of NHC.Intracellular levels of the parental compounds and phosphorylated metabolites are measured using LC-MS/MS. Small amounts of NHC-monophosphate (MP) and NHC-diphosphate (DP; HY-135867D) can be observed, while NHC-triphosphate remains the most abundant metabolite..
Uridine 5'-(trihydrogen diphosphate), 4-oxime (9CI)
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/08/19 | HY-135867D | NHC-diphosphate | 39023-73-9 | 1 mg | 3800元 |
| 2024/08/19 | HY-135867D | NHC-diphosphate | 39023-73-9 | 5 mg | 8000元 |
Uridine 5'-(trihydrogen diphosphate), 4-oxime (9CI)
生产厂家
39023-73-9, Uridine 5'-(trihydrogen diphosphate), 4-oxime (9CI) 相关搜索:
- C9H15N3O12P2
- 39023-73-9
- NHC-diphosphate
- Uridine 5'-(trihydrogen diphosphate), 4-oxime (9CI)